Buffalo Bills vs. Miami Dolphins: Experts release early Week 10 projections [2025]

The Buffalo Bills and Miami Dolphins will meet in Week 10 of the NFL season at Hard Rock Stadium on Sunday, November 9, 2025, starting at 1:00PM ET.

Initial simulations from Dimers' trusted NFL model favor the Bills as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Bills vs. Dolphins predictions page.

Buffalo vs. Miami early predictions

Leveraging trusted machine learning and analysis, we have simulated the Bills vs. Dolphins game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Bills 78%, Dolphins 22%
• Predicted final score: Bills 28-20 Dolphins
• Spread: Bills (-9.5) 47%, Dolphins (+9.5) 53%
• Total points (49.5): Over 47%, Under 53%

As of November 3, 2025, these Bills-Dolphins figures and predictions reflect the latest data and insights available.

Bills vs. Dolphins Week 10 details

The NFL Week 10 matchup between the Dolphins and Bills at Hard Rock Stadium is scheduled for November 9, 2025.

• Who: Buffalo Bills vs. Miami Dolphins
• Date: Sunday, November 9, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Hard Rock Stadium

Bills vs. Dolphins opening odds

We've researched the best betting odds across America for this Week 10 game, which are listed here:

• Spread: Bills -9.5 (-110), Dolphins +9.5 (-110)
• Moneyline: Bills -470, Dolphins +400
• Total: Over/Under 49.5 (-120/-102)

Odds may continue to move—track live changes via our NFL odds page.

Anytime touchdown scorer predictions

Early NFL player projections for Week 10 highlight the top candidates to score a TD in Bills-Dolphins in Week 10:

Buffalo Bills

• James Cook: 57.2% probability
• Khalil Shakir: 37.4% probability
• Josh Allen: 30.3% probability

Miami Dolphins

• De'Von Achane: 53.4% probability
• Jaylen Waddle: 37.8% probability
• Malik Washington: 28.7% probability

Bills vs Dolphins player props

James Cook is projected to lead rushing for the Bills, while De'Von Achane is expected to pace the Dolphins on the ground.

In the receiving game, our projections favor Buffalo's Khalil Shakir and Miami's Jaylen Waddle as the likely leaders for each team.

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Conclusion

We predict the Bills, with a 78% win probability, will likely beat the Dolphins in Week 10 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Bills vs. Dolphins matchup, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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