Arizona Cardinals vs. Houston Texans: Experts release early Week 15 preview [2025]

The Arizona Cardinals and Houston Texans will meet in Week 15 of the NFL season at NRG Stadium on Sunday, December 14, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Texans as the most likely winner of this cross-conference battle.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Cardinals vs. Texans predictions page.

Arizona vs. Houston early predictions

Leveraging trusted machine learning and analysis, we have simulated the Cardinals vs. Texans game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Cardinals 26%, Texans 74%
• Predicted final score: Cardinals 18-24 Texans
• Spread: Cardinals (+7) 57%, Texans (-7) 43%
• Total points (43.5): Over 48%, Under 52%

As of December 8, 2025, these Cardinals-Texans calculations and predictions reflect the latest data and insights available.

Cardinals vs. Texans Week 15 details

The NFL Week 15 game between the Texans and Cardinals at NRG Stadium is scheduled for December 14, 2025.

• Who: Arizona Cardinals vs. Houston Texans
• Date: Sunday, December 14, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: NRG Stadium

Cardinals vs. Texans opening odds

We've researched the best betting odds across America for this Week 15 game, which are listed here:

• Spread: Cardinals +7 (-105), Texans -7 (-115)
• Moneyline: Cardinals +275, Texans -320
• Total: Over/Under 43.5 (-105/-115)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Texans, with a 74% win probability, will likely beat the Cardinals in Week 15 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Cardinals vs. Texans matchup, with human oversight maintaining high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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