NBA picks today: Thursday's best bets include Nuggets vs. Thunder play [10/22/2026]
Get best NBA picks today and best bets for Thursday, October 22, 2026.

Today’s NBA picks for October 22, 2026 are here, with Nuggets vs. Thunder and Cavaliers vs. 76ers among the top plays identified by our model across Thursday’s NBA play.
Dimers’ predictive analytics engine runs 24/7, searching the latest basketball odds to find real betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of NBA picks tonight [10/22, updated 3:37AM ET]
Below, you’ll find today’s NBA best bets, ranked by edge for Thursday, October 22, 2026.
Nuggets +7.5 (-104)
- Edge: 5.4%
- Probability: 56.4%
- Matchup: Nuggets vs. Thunder (9:30PM ET)
Our model has identified value on Nuggets +7.5 at -104 odds. A 56.4% probability produces an edge of 5.4%, making this the strongest play for today's NBA slate.
76ers ML (-150)
- Edge: 3.5%
- Probability: 61.4%
- Matchup: Cavaliers vs. 76ers (7:00PM ET)
76ers ML carries a 3.5% edge and a probability of 61.4% at -150 odds, according to our model.
Nuggets vs. Thunder Under 235.5 points (49¢)
- Edge: 3.3%
- Probability: 52.3%
- Matchup: Nuggets vs. Thunder (9:30PM ET)
Nuggets vs. Thunder Under 235.5 points at 49¢ odds shows a 3.3% edge, supported by a 52.3% probability in simulations.
Cavaliers vs. 76ers under 235.5 points (+104)
- Edge: 2.9%
- Probability: 51.9%
- Matchup: Cavaliers vs. 76ers (7:00PM ET)
A 2.9% edge and 51.9% probability make Cavaliers vs. 76ers under 235.5 points a value play in the Cavaliers vs. 76ers matchup, per our model.
NBA best bets summary: Thursday, 10/22/2026
As of 3:37AM ET, here are our top NBA bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Prob. |
|---|---|---|---|---|
| Nuggets vs. Thunder | Nuggets +7.5 | -104 @ BetRivers | 5.4% | 56.4% |
| Cavaliers vs. 76ers | 76ers ML | -150 @ Caesars | 3.5% | 61.4% |
| Nuggets vs. Thunder | Under 235.5 Points | 49¢ @ Polymarket | 3.3% | 52.3% |
| Cavaliers vs. 76ers | Under 235.5 points | 49¢ @ Novig | 2.9% | 51.9% |
List of upcoming NBA games to bet on [10/22/2026]
- Cavaliers vs. 76ers (7:00PM ET, Thursday)
- Nuggets vs. Thunder (9:30PM ET, Thursday)
Conclusion
Our NBA best bets are locked and loaded for October 22, 2026, featuring plays such as Nuggets +7.5 vs. Thunder and 76ers ML. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.



