Oregon vs. Southern California Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Oregon vs. Southern California NCAAF game on September 26, 2026. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

FINAL
COLLEGE FOOTBALL
FINAL
CFB sport icon
COLLEGE FOOTBALL
Oregon
41
27
Los Angeles Memorial Coliseum
Southern California
Los Angeles Memorial Coliseum
Live Probabilities
Win %
  • Oregon
    100%
  • Southern California
    0%
Win Probability
TEAM1234T
Oregon
3 10 14 14 41
Southern California
0 10 10 7 27
1 0 2 0 3 0 4 0 5 0 4 0 3 0 2 0 1 0 1 0 2 0 3 0 4 0 5 0 4 0 3 0 2 0 1 0
Southern California
Oregon
2nd and 11 at the ORE 19
Last Play
D.Raiola kneels at the ORE 19.

Oregon vs. Southern California: Detailed Breakdown

Matchup Overview

  • Teams: Oregon vs. Southern California
  • Date: Saturday, September 26, 2026
  • Time: 7:30 PM ET
  • Venue: Los Angeles Memorial Coliseum

Current betting odds

  • Spread: Oregon favored at -7.5
  • Total (Over/Under): 55.5
  • Moneyline Odds: Oregon -180, Southern California +250

Dimers' win probabilities

  • Oregon: 64%
  • Southern California: 36%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Oregon 32-28 Southern California.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Oregon a win probability of 64%, while Southern California has a win probability of 36%.

Summary

According to our analysis, Oregon is more likely to beat Southern California in CFB action at Los Angeles Memorial Coliseum on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Oregon vs. Southern California predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert college football predictions and the best college football bets today for more insights and betting opportunities.

Our in-depth analysis includes college football player props and college football futures, as well as constantly updated college football odds and the latest college football news.