William & Mary vs. Duke Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the William & Mary vs. Duke NCAAF game on September 26, 2026. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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William & Mary
Predicted score
10
:
53
Brooks Field at Wallace Wade Stadium
Duke
Brooks Field at Wallace Wade Stadium
Pre-Game Probabilities Last Update:

Spread

William & Mary +43.5
Spread
  • William & Mary
    51.6%
  • Duke
    48.4%

William & Mary vs. Duke: Detailed Breakdown

Matchup Overview

  • Teams: William & Mary vs. Duke
  • Date: Saturday, September 26, 2026
  • Time: 3:30 PM ET
  • Venue: Brooks Field at Wallace Wade Stadium

Current betting odds

  • Spread: Duke favored at -43.5
  • Total (Over/Under): 62.5
  • Moneyline Odds: William & Mary +NaN, Duke +NaN

Dimers' win probabilities

  • William & Mary: 1%
  • Duke: 99%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is William & Mary 10-53 Duke.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives William & Mary a win probability of 1%, while Duke has a win probability of 99%.

Summary

According to our analysis, Duke is more likely to beat William & Mary in CFB action at Brooks Field at Wallace Wade Stadium on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our William & Mary vs. Duke predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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