Louisiana-Lafayette vs. Louisiana-Monroe prediction favors Louisiana-Lafayette to win in college football Week 11 [2026]

Using innovative machine learning and statistical analysis, we have re-simulated the result of Louisiana-Lafayette vs. Louisiana-Monroe, forming part of our college football predictions coverage.

Our leading predictive model gives Louisiana-Lafayette a 76.4% chance of defeating Louisiana-Monroe. Our predicted final score has Louisiana-Lafayette winning 29-20. According to our model, Louisiana-Monroe (+10.5) has a 53.8% chance of covering the spread, while the 48.5-point over/under has a 53.5% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Louisiana-Lafayette -10.5 (+104) / Louisiana-Monroe +10.5 (-108)
• Moneyline: Louisiana-Lafayette -365, Louisiana-Monroe +344
• Total: Over/Under 48.5 (-111/+102)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Louisiana-Monroe +10.5 @ 52¢ via Novig
• Moneyline: Louisiana-Monroe @ 23¢ via Novig
• Total: Over 48.5 @ 53¢ via Novig

According to our college football best bets, the top play to make on this game is Louisiana-Monroe +10.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Thursday's college football matchup between Louisiana-Monroe and Louisiana-Lafayette at JPS Field at Malone Stadium is scheduled to start at 9:00 PM ET.

• Who: Louisiana-Lafayette vs. Louisiana-Monroe
• Date: Thursday, November 12, 2026
• Time: 9:00 PM ET/6:00 PM PT
• Venue: JPS Field at Malone Stadium

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Conclusion

We predict Louisiana-Lafayette, with a 76.4% win probability, will likely beat Louisiana-Monroe in Thursday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary college football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.