Southeastern Louisiana vs. Northwestern State prediction favors Southeastern Louisiana to win in college football Week 4 [2026]

Using innovative machine learning and statistical analysis, we have re-simulated the result of Southeastern Louisiana vs. Northwestern State, forming part of our college football predictions coverage.

Our famous predictive model currently gives Southeastern Louisiana a 97.9% chance of defeating Northwestern State. Our predicted final score has Southeastern Louisiana winning 47-12. According to our model, Northwestern State (+37.5) has a 54.2% chance of covering the spread, while the 60.5-point over/under has a 51.4% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Southeastern Louisiana -37.5 (-110) / Northwestern State +37.5 (-113)
• Moneyline: Southeastern Louisiana , Northwestern State

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Under @ -110 via Bet365

According to our college football best bets, the top play to make on this game is Northwestern State +37.5.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between Northwestern State and Southeastern Louisiana at Harry Turpin Stadium is scheduled to start at 7:00 PM ET.

• Who: Southeastern Louisiana vs. Northwestern State
• Date: Saturday, September 26, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Harry Turpin Stadium

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Conclusion

We predict Southeastern Louisiana, with a 97.9% win probability, will likely beat Northwestern State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.