Missouri State vs. Florida International prediction favors Florida International to win in college football Week 10 [2026]

Using powerful machine learning and data analysis, we have re-simulated the result of Missouri State vs. Florida International, forming part of our college football predictions coverage.

Our leading predictive model currently gives Florida International a 64.0% chance of defeating Missouri State. Our predicted final score has Florida International winning 27-22. According to our model, Missouri State (+4.5) has a 50.3% chance of covering the spread, while the 49.5-point over/under has a 51.9% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Missouri State +4.5 (+106) / Florida International -4.5 (-108)
• Moneyline: Missouri State +182, Florida International -190
• Total: Over/Under 49.5 (-102/-102)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Missouri State +4.5 @ 48¢ via Novig
• Moneyline: Missouri State @ 36¢ via Novig
• Total: Over 49.5 @ 50¢ via Novig

According to our best college football bets, the top play to make on this game is Missouri State +4.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between Florida International and Missouri State at Pitbull Stadium is scheduled to start at 4:00 PM ET.

• Who: Missouri State vs. Florida International
• Date: Saturday, November 7, 2026
• Time: 4:00 PM ET/1:00 PM PT
• Venue: Pitbull Stadium

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Conclusion

We predict Florida International, with a 64.0% win probability, will likely beat Missouri State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary college football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.