Lafayette vs. Columbia prediction: Why Columbia is favored to win in college football Week 3 [2026]

Using trusted machine learning and statistical analysis, we have re-simulated the result of Lafayette vs. Columbia, forming part of our college football predictions coverage.

Our independent predictive model currently gives Columbia a 61.8% chance of defeating Lafayette. Our predicted final score has Columbia winning 26-22. According to our model, Columbia (-2.5) has a 54.3% chance of covering the spread, while the over/under total of 47.5 points has a 52.7% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Lafayette +2.5 (-105) / Columbia -2.5 (-114)
• Moneyline: Lafayette +120, Columbia -140
• Total: Over/Under 47.5 (-112/-105)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Columbia -2.5 @ -114 via DraftKings
• Moneyline: Columbia @ -140 via bet365
• Total: Over 47.5 @ -112 via DraftKings

According to our college football best bets, the top play to make on this game is Columbia to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between Columbia and Lafayette at Robert K. Kraft Field at Lawrence A. Wien Stadium is scheduled to commence at 12:00 PM ET.

• Who: Lafayette vs. Columbia
• Date: Saturday, September 19, 2026
• Time: 12:00 PM ET/9:00AM PT
• Venue: Robert K. Kraft Field at Lawrence A. Wien Stadium

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Conclusion

We predict Columbia, with a 61.8% win probability, will likely beat Lafayette in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.