DePaul vs. Notre Dame prediction, odds, pick for Nov. 14, 2026

Notre Dame is favored to beat DePaul at Colonial Hall on Saturday (1:00 PM ET), according to Dimers' women's basketball model.

Our DePaul vs. Notre Dame prediction gives the Blue Demons a 99.3% chance of winning, while the latest odds suggest there's betting value on the under 158.5 points.

DePaul vs. Notre Dame key predictions

• Predicted score: Notre Dame 89-58 DePaul
• Notre Dame win probability: 99.3%
• DePaul win probability: 0.7%
• Notre Dame -30.5 spread: 52.2% cover probability
• Under 158.5 points: 58.3% probability

Our women's basketball predictions start with projected final scores for both teams, based on each team's recent and long-term efficiency at both ends of the floor, adjusted for the matchup.

We pair those projections with historical scoring trends to calculate win, spread, and total probabilities, then compare them with current odds to find betting value.

DePaul vs. Notre Dame odds

Here are the best available odds across the moneyline, spread, and total points markets we track.

• DePaul moneyline: +5000 (DraftKings)
• Notre Dame moneyline: -100000 (DraftKings)
• DePaul +30.5: -110 (DraftKings)
• Notre Dame -30.5: -108 (BetRivers)
• Over 158.5 points: -112 (FanDuel)
• Under 158.5 points: -105 (DraftKings)

Odds are subject to change and may vary by location.

DePaul vs. Notre Dame pick: Under 158.5 (-105)

Our model makes Notre Dame the more likely winner, but our best value bet is the under 158.5 total points at -105 on DraftKings.

Those odds give the under an implied probability of 51.2%, while our model rates it at 58.3%.

That's a 7.1% edge, the largest across the moneyline, spread, and total points markets.

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DePaul vs. Notre Dame game details

• Matchup: DePaul Blue Demons vs. Notre Dame
• Date: Saturday, November 14, 2026
• Time: 1:00 PM ET
• Venue: Colonial Hall

About this prediction

This preview uses predictions from our women's basketball models, presented through a template written by our editorial team. Matchup details fill in automatically.

Predictions are estimates, not guarantees, and can change as new information comes in, such as injury news or lineup changes. Learn how our predictions work.

Dimers encourages responsible gambling.