Golden Knights vs. Blues prediction, odds and best bet for Oct. 22, 2026

The Vegas Golden Knights are favored to beat the St. Louis Blues on Thursday, according to Dimers' NHL pregame model.

Our Golden Knights vs. Blues prediction gives Vegas a 52.3% chance of winning at Enterprise Center, but the latest odds suggest the Blues may offer better betting value despite being the underdog.

Golden Knights vs. Blues: Key predictions

• Golden Knights win probability: 52.3%
• Blues win probability: 47.7%
• Blues +1.5 puck line: 69.2% cover probability
• Under 6.5 goals: 56.2% probability

Dimers' NHL pregame model estimates how many goals each team is likely to score, accounting for factors such as recent form, shooting and save percentages, home-ice advantage, and rest.

These projections power our NHL predictions, which show the probability of each team winning, covering the puck line, and the total goals going over or under the betting line.

Golden Knights vs. Blues odds

Here are the best available odds across the moneyline, puck line, and total goals markets monitored by Dimers.

• Golden Knights moneyline: 54¢ (Novig)
• Blues moneyline: 46¢ (Novig)
• Golden Knights -1.5: 32¢ (Novig)
• Blues +1.5: 69¢ (Novig)
• Over 6.5 goals: +115 (theScore Bet)
• Under 6.5 goals: -133 (bet365)

Odds are subject to change and may vary by location.

Best value bet: Blues moneyline (46¢)

The Golden Knights may be more likely to win, but Dimers' top value bet is the Blues moneyline at 46¢, available at Novig.

Those odds imply the Blues have a 46.5% chance of winning, while our model puts that probability at 47.7%.

That's a 1.2% edge in the Blues' favor, the largest across the moneyline, puck line, and total goals markets based on Dimers' probabilities and the best available odds.

Golden Knights vs. Blues goal-scorer predictions

Unlike our NHL pregame model, Dimers' NHL player props model simulates each matchup 10,000 times to estimate goal-scoring probabilities, factoring in expected player usage, lineup changes, the opposing team, and projected team goals.

Mark Stone of the Golden Knights leads Thursday's anytime goal-scorer projections at 34.0%, followed by St. Louis's Dylan Holloway (31.8%). Stone also leads the first goal-scorer projections at 6.8%.

Most likely anytime goal-scorers

• Mark Stone (Golden Knights): 34.0%
• Dylan Holloway (Blues): 31.8%
• Trevor Connelly (Golden Knights): 31.6%
• Robert Thomas (Blues): 30.6%
• Jimmy Snuggerud (Blues): 29.4%

First goal-scorer predictions

• Mark Stone (Golden Knights): 6.8%
• Jimmy Snuggerud (Blues): 6.4%
• Dylan Holloway (Blues): 6.1%
• Trevor Connelly (Golden Knights): 6.1%
• Jack Eichel (Golden Knights): 5.7%

These are model probabilities, not betting recommendations. Compare projections with available odds to assess potential value.

Unlock all Golden Knights vs. Blues predictions with Dimers Pro

Get the complete picture for Thursday's matchup with Dimers Pro, including:

• Best bets for the moneyline, puck line, and total goals markets.
• Full anytime and first goal-scorer probabilities for players on both teams.
• High-value player props across anytime goal-scorer, first goal-scorer, shots on goal, points, and assists markets.

See our full range of Golden Knights vs. Blues predictions.

Golden Knights vs. Blues game details

• Matchup: Vegas Golden Knights vs. St. Louis Blues
• Date: Thursday, October 22, 2026
• Puck drop: 8:00 PM ET/5:00 PM PT
• Venue: Enterprise Center

About this prediction

This preview uses predictions from Dimers' proprietary NHL models, presented through a human-written template. Matchup-specific information is populated automatically.

Predictions are estimates, not guarantees, and may change as new information becomes available. Learn more about how Dimers predictions work.

Dimers encourages responsible gambling.