Blue Jackets vs. Sabres prediction, odds, pick for Nov. 6, 2026

The Buffalo Sabres are favored to beat the Columbus Blue Jackets at KeyBank Center on Friday (7:00 PM ET), according to Dimers' NHL model.

Our Blue Jackets vs. Sabres prediction gives Buffalo a 59.7% chance of winning, but the latest odds suggest there's betting value on the Blue Jackets as the underdog.

Blue Jackets vs. Sabres key predictions

• Sabres win probability: 59.7%
• Blue Jackets win probability: 40.3%
• Blue Jackets +1.5 puck line: 62.5% cover probability
• Under 6.5 goals: 54.5% probability

Our NHL predictions estimate how many goals each team is likely to score, accounting for factors such as recent performance, shooting and save percentages, home-ice advantage, and rest.

We then calculate the probability of each team winning and covering the puck line, plus the chance the game goes over or under the total, and compare those probabilities with the latest odds to find betting value.

Blue Jackets vs. Sabres odds

Here are the best available odds across the moneyline, puck line, and total goals markets we track. Novig has the best price in every market for this game.

• Blue Jackets moneyline: 39¢ (Novig)
• Sabres moneyline: 61¢ (Novig)
• Blue Jackets +1.5: 62¢ (Novig)
• Sabres -1.5: 39¢ (Novig)
• Over 6.5 goals: 47¢ (Novig)
• Under 6.5 goals: 53¢ (Novig)

Odds are subject to change and may vary by location.

Blue Jackets vs. Sabres pick: Blue Jackets ML (39¢)

Our model makes the Sabres the likelier winner, but our best value bet is the Blue Jackets moneyline at 39¢ on Novig.

Those odds give the Blue Jackets an implied win probability of 39.0%, while our model puts it at 40.3%.

That's a 1.3% edge, the largest across the moneyline, puck line, and total goals markets for this game.

Blue Jackets vs. Sabres goal-scorer predictions

Our NHL player props model simulates each matchup 10,000 times to estimate goal-scoring probabilities, factoring in expected player usage, lineup changes, opponent strength, and projected team goals.

Tage Thompson of the Sabres leads the anytime goal-scorer projections for Friday's game at 40.3%, followed by Columbus's Adam Fantilli (28.8%). Thompson also leads the first goal-scorer projections at 7.8%.

Most likely anytime goal-scorers

1. Tage Thompson (Sabres): 40.3%
2. Adam Fantilli (Blue Jackets): 28.8%
3. Jack Quinn (Sabres): 28.7%
4. Josh Doan (Sabres): 23.2%
5. Charlie Coyle (Blue Jackets): 23.0%

First goal-scorer predictions

1. Tage Thompson (Sabres): 7.8%
2. Jack Quinn (Sabres): 6.2%
3. Adam Fantilli (Blue Jackets): 5.6%
4. Matthew Knies (Blue Jackets): 4.3%
5. Charlie Coyle (Blue Jackets): 4.3%

These are model probabilities, not betting recommendations. Compare projections with available odds to assess potential value.

Get every Blue Jackets vs. Sabres prediction with Dimers Pro

Dimers Pro members get full access to our Blue Jackets vs. Sabres predictions, including:

• Best bets across the moneyline, puck line, and total goals markets
• Full anytime and first goal-scorer probabilities for players on both teams
• Player prop edges for anytime goal-scorer, first goal-scorer, shots on goal, points, and assists markets

Blue Jackets vs. Sabres game details

• Matchup: Columbus Blue Jackets vs. Buffalo Sabres
• Date: Friday, November 6, 2026
• Puck drop: 7:00 PM ET
• Venue: KeyBank Center

About this prediction

This preview uses predictions from our NHL models, presented through a template written by our editorial team. Matchup details fill in automatically.

Predictions are estimates, not guarantees, and can change as new information comes in, such as injury news or starting goaltender confirmations. Learn how our predictions work.

Dimers encourages responsible gambling.