Dolphins vs. Bills: NFL Week 11 Prediction, Picks & Odds

Dimers' Dolphins vs. Bills prediction for Sunday, November 22, 2026. Win probabilities, projected final score, current odds, and picks from our NFL machine learning models.
NFL
NFL sport icon
NFL
Dolphins
Predicted score
18
:
30
Highmark Stadium
Bills
Highmark Stadium
Pre-Game Probabilities Last updated:

Spread

Dolphins +12.5
Spread
  • Dolphins
    50.9%
    CaesarsCaesars
  • Bills
    49.1%
    CaesarsCaesars

Dolphins vs. Bills: Detailed Breakdown

Matchup overview: NFL Week 11

  • Teams: Miami Dolphins vs. Buffalo Bills
  • Date: Sunday, November 22, 2026
  • Time: 1:00PM ET
  • Venue: Highmark Stadium

Current betting odds

  • Spread: Dolphins (+12.5, -115), Bills (-12.5, -115)
  • Moneyline: Dolphins +500, Bills -800
  • Total (Over/Under): 48.5 points (-115/-115)

Dimers’ win probabilities

  • Dolphins: 15.4%
  • Bills: 84.6%

These probabilities come from two machine learning models that assess more than 100 data points for each NFL matchup, combining their outputs to project all our major betting markets.

Projected final score

Our predicted final score for this NFL matchup is Dolphins 17-29 Bills.

This prediction draws on each team's scoring trends and player stats, weighed across both of our data models

Our Prediction: Who Wins?

The numbers give the Dolphins a win probability of 15.4%, while the Bills have a win probability of 84.6%.

Summary

The Dolphins face off against the Bills in the NFL at Highmark Stadium on Sunday, November 22, 2026.

Our Dolphins vs. Bills predictions, built on real-time data and matchup-specific modeling, help guide your decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert NFL predictions and the best NFL bets today, while our in-depth analysis includes NFL props, NFL futures, NFL odds, and the latest NFL news.