Jacksonville Jaguars vs. Tennessee Titans: Experts release early Week 10 preview [2026]

The Jacksonville Jaguars and Tennessee Titans will meet in Week 10 of the NFL season at Nissan Stadium on Sunday, November 15, 2026, starting at 1:00 PM ET.

Initial simulations from Dimers' trusted NFL model favor the Jaguars as the most likely winner of this AFC South rivalry matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Jaguars vs. Titans predictions page.

Jacksonville vs. Tennessee early predictions

Leveraging trusted machine learning and analysis, we have simulated the Jaguars vs. Titans game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Jaguars 79.9%, Titans 20.1%
• Predicted final score: Jaguars 28-18 Titans
• Spread: Jaguars (-10.5) 48.7%, Titans (+10.5) 51.3%
• Total points (47.5): Over 50.0%, Under 50.0%

As of November 9, 2026, these Jaguars-Titans numbers and predictions reflect the latest data and insights available.

Jaguars vs. Titans Week 10 details

Sunday's game between the Titans and Jaguars at Nissan Stadium is scheduled for November 15, 2026.

• Who: Jacksonville Jaguars vs. Tennessee Titans
• Date: Sunday, November 15, 2026
• Time: 1:00 PM ET/10:00 AM PT
• Venue: Nissan Stadium

Jaguars vs. Titans opening odds

We've researched the best betting odds across America for this Week 10 game, which are listed here:

• Spread: Jaguars -10.5 (+106), Titans +10.5 (-117)
• Moneyline: Jaguars -456, Titans +450
• Total: Over/Under 47.5 (+106/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Jaguars, with a 79.9% win probability, will likely beat the Titans in Week 10 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Jaguars vs. Titans game, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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