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San Francisco 49ers vs. Seattle Seahawks: Experts release early Divisional Round predictions [2026]

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Written by Jason Bevilacqua

Get early predictions for the upcoming 49ers vs Seahawks NFL game.

San Francisco 49ers-Seattle Seahawks Early Predictions and Betting Preview.
Lumen Field sets the stage for the NFL matchup between the San Francisco 49ers and Seattle Seahawks this Saturday.

The San Francisco 49ers and Seattle Seahawks will meet in the Divisional Round at Lumen Field on Saturday, January 17, 2026, starting at 8:00 PM ET.

Early simulations from Dimers' trusted NFL model favor the Seahawks as the most likely winner of this NFC West rivalry clash.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive 49ers vs. Seahawks predictions page.

San Francisco vs. Seattle early predictions

Leveraging trusted machine learning and analysis, we have simulated the Niners vs. Seahawks game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

  • Straight up win probabilities: 49ers 25%, Seahawks 75%
  • Predicted final score: 49ers 19-25 Seahawks
  • Spread: 49ers (+7.5) 56%, Seahawks (-7.5) 44%
  • Total points (45.5): Over 45%, Under 55%

As of January 13, 2026, these 49ers-Seahawks calculations and predictions reflect the latest data and insights available.

 

Niners vs. Seahawks Divisional Round details

Saturday's action between the Seahawks and 49ers at Lumen Field is scheduled for January 17, 2026.

Niners vs. Seahawks opening odds

We've researched the best betting odds across America for this Divisional Round clash, which are listed here:

  • Spread: 49ers +7.5 (-110), Seahawks -7.5 (-108)
  • Moneyline: 49ers +310, Seahawks -355
  • Total: Over/Under 45.5 (-108/-105)

Odds may continue to move—track live changes via our NFL odds page.

Anytime touchdown scorer predictions

Early NFL player projections for the Divisional Round highlight the top candidates to score a TD in Niners-Seahawks in Week 20:

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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