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76ers vs. Thunder prediction: Oklahoma City favored to win Sunday's NBA matchup [12/28/2025]

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Written by Dave Garofolo

Get Philadelphia 76ers vs Oklahoma City Thunder predictions for NBA Sunday.

Philadelphia 76ers-Oklahoma City Thunder Predictions and Game Preview.
Philadelphia 76ers vs. Oklahoma City Thunder NBA prediction for Sunday, December 28, 2025.

The Oklahoma City Thunder will square off with the Philadelphia 76ers in NBA action at Paycom Center on Sunday, beginning at 3:30 PM ET.

Based on updated simulation results and today’s injury updates, Dimers' advanced NBA model projects the Thunder as the most likely winner of the 76ers vs. Thunder game.

This prediction follows the latest NBA Injury Report, which suggests the Thunder lineup will feature stars like Shai Gilgeous-Alexander, Jalen Williams and Chet Holmgren, while the 76ers will rely on Tyrese Maxey, Paul George and VJ Edgecombe.

This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Sixers vs. Sixers prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Sunday's NBA matchup between the 76ers and Thunder 10,000 times as part of our NBA predictions coverage.

Our leading predictive model currently gives the Thunder an 87% chance of beating the 76ers. Our predicted final score has the Thunder winning 119-106.

According to our model, the 76ers (+15.5) have a 58% chance of covering the spread, while the 225.5-point over/under has a 51% chance of going over.

 

76ers vs. Thunder odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type 76ers Thunder
Spread +15.5 (-110) -15.5 (-108)
Moneyline +700 -1000
Total o225.5 (-110) u225.5 (-110)

All odds are correct at the time of publication and are subject to change.

76ers vs. Thunder picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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