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76ers vs. Pacers prediction: Why Philadelphia is favored to win Friday's NBA matchup [4/10/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Philadelphia 76ers vs Indiana Pacers predictions for NBA Friday.
The Indiana Pacers will square off with the favored Philadelphia 76ers in NBA action at Gainbridge Fieldhouse on Friday, commencing at 7:30 PM ET.
Based on updated simulations and today’s injury news, Dimers' proven NBA model predicts the 76ers as the most likely winner of the 76ers vs. Pacers game.
This prediction follows the latest NBA Injury Report, which suggests the Pacers lineup will feature players like Pascal Siakam, Jarace Walker and Andrew Nembhard, while the 76ers will rely on Tyrese Maxey, Paul George and VJ Edgecombe.
This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Sixers vs. Sixers prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Friday's NBA matchup between the 76ers and Pacers, forming part of our NBA predictions coverage.
Our independent predictive model gives the 76ers an 86% chance of defeating the Pacers. Our predicted final score has the 76ers winning 122-109.
According to our model, the Pacers (+15) have a 58% chance of covering the spread, while the over/under total of 233 points has a 51% chance of staying under.
76ers vs. Pacers odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | 76ers | Pacers |
|---|---|---|
| Spread | -15 (-105) | +15 (-114) |
| Moneyline | -1200 | +750 |
| Total | o233 (-110) | u233 (-110) |
All odds are correct at the time of publication and are subject to change.
76ers vs. Pacers picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pacers +15 | -114 |
| Moneyline | Pacers | +750 |
| Total | Under 233 | -110 |
According to our best NBA bets for Friday, the top play to make on this game is Pacers +15 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
76ers vs. Pacers player props
Betting on Philadelphia vs. Indiana NBA player props? We have crunched the numbers to project how each team's leading players will perform at Gainbridge Fieldhouse.
Tyrese Maxey is expected to lead the 76ers with 28 points, 4 rebounds and 7 assists, while Pascal Siakam is projected to have 21 points, 5 rebounds and 3 assists for the Pacers.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
76ers prediction
Our model's projected player stats for the 76ers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Tyrese Maxey | 28 | 4 | 7 | 3 | 51 |
| Paul George | 21 | 6 | 5 | 3 | 41 |
| VJ Edgecombe | 17 | 6 | 5 | 2 | 36 |
| Kelly Oubre | 14 | 5 | 2 | 1 | 27 |
| Quentin Grimes | 12 | 3 | 3 | 1 | 24 |
Pacers prediction
Projected points, rebounds, assists and three-pointers made for the Pacers:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Pascal Siakam | 21 | 5 | 3 | 2 | 37 |
| Jarace Walker | 15 | 6 | 4 | 2 | 33 |
| Andrew Nembhard | 15 | 3 | 6 | 2 | 32 |
| Aaron Nesmith | 14 | 4 | 2 | 2 | 27 |
| Obi Toppin | 10 | 4 | 2 | 1 | 21 |
Sixers vs. Pacers game-day updates and essential details
Friday's matchup between the Pacers and 76ers at Gainbridge Fieldhouse is scheduled to start at 7:30 PM ET.
- Who: Philadelphia 76ers vs. Indiana Pacers
- Date: Friday, April 10, 2026
- Time: 7:30 PM ET/4:30PM PT
- Venue: Gainbridge Fieldhouse
Conclusion
We predict the 76ers, with an 86% win probability, will likely beat the Pacers in Friday's NBA matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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