Knicks vs. Trail Blazers Prediction: New York Predicted to Win Wednesday's NBA Game [3/12/2025]

The Portland Trail Blazers will face the New York Knicks in NBA action at Moda Center on Wednesday, commencing at 10:00PM ET.

Based on the latest simulations and today’s injury news, Dimers' advanced NBA model (see Dimers Pro for full access) predicts the Knicks as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's New York-Portland game 10,000 times," said Damien Souness from Dimers.

"With the latest updates and numerous other variables, we estimate the Knicks' chance of winning at 65%, with the Trail Blazers at 35%."

This prediction follows the latest NBA Injury Report, which suggests the Trail Blazers lineup will feature stars like Anfernee Simons, Deni Avdija and Shaedon Sharpe, while the Knicks will look to Karl-Anthony Towns, Mikal Bridges and OG Anunoby.

For further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Knicks vs. Trail Blazers predictions page.

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Trail Blazers vs. Knicks Prediction: Who Will Win, Cover the Spread?

Using powerful machine learning and data, we have simulated the result of Wednesday's NBA matchup between the Knicks and Trail Blazers 10,000 times as part of our NBA predictions coverage.

Our independent predictive model currently gives the Knicks a 65% chance of defeating the Trail Blazers. Our predicted final score has the Knicks winning 116-112.

According to our model, the Knicks (-4) have a 51% chance of covering the spread, while the 228.5-point over/under has an equal 50-50 chance of hitting.

Knicks vs. Trail Blazers Odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type	Knicks	Trail Blazers
Spread	-4 (-108)	+4 (-108)
Moneyline	-175	+162
Total	o228.5 (-105)	u228.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Knicks vs. Trail Blazers Picks and Best Bets

Our model's strongest edge in today's Knicks vs. Trail Blazers matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best NBA picks for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Knicks vs. Trail Blazers Player Props

Betting on New York vs. Portland NBA prop bets? We use the best information available to project how each team's leading players will perform at Moda Center.

Karl-Anthony Towns is expected to lead the Knicks with 24 points, 14 rebounds and 4 assists, while Anfernee Simons is projected to have 22 points, 3 rebounds and 5 assists for the Trail Blazers.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Knicks vs. Blazers Game-Day Updates and Essential Details

Wednesday's action between the Trail Blazers and Knicks at Moda Center is scheduled to begin at 10:00PM ET.

• Who: New York Knicks vs. Portland Trail Blazers
• Date: Wednesday, March 12, 2025
• Time: 10:00PM ET/7:00PM PT
• Venue: Moda Center

Dimers.com's comprehensive preview of Wednesday's Knicks vs. Trail Blazers matchup includes our prediction, picks and the latest betting odds.

Before making any New York vs. Portland picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

Conclusion

We predict the Knicks, with a 65% win probability, will likely beat the Trail Blazers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Knicks vs. Trail Blazers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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