NBA picks today: Monday's best bets highlight Pistons vs. Trail Blazers play [12/22/2025]

Today’s NBA picks for December 22, 2025 are here, with Pistons vs. Trail Blazers among the top plays identified by our model across Monday’s NBA play.

Dimers’ predictive analytics engine runs 24/7, scanning the latest basketball odds to unearth real betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of NBA picks tonight [12/22, updated 9:31PM ET]

Below, you’ll find today’s best basketball bets, ranked by edge for Monday, December 22, 2025.

Trail Blazers +5.5 (+100)

• Edge: 2.5%
• Probability: 52.5%
• Matchup: Pistons vs. Trail Blazers (10:00PM ET, Monday)

Our model has identified value on Trail Blazers +5.5 at +100 odds. A 52.5% probability produces an edge of 2.5%, making this the strongest play for today's NBA slate.

Hawks ML (-166)

• Edge: 3.4%
• Probability: 65.8%
• Matchup: Bulls vs. Hawks (7:30PM ET, Tuesday)

A 3.4% edge and 65.8% probability make Hawks at the moneyline at a value play in the Bulls vs. Hawks matchup, per our model.

Hornets ML (-225)

• Edge: 2.7%
• Probability: 71.9%
• Matchup: Wizards vs. Hornets (7:00PM ET, Tuesday)

Hornets ML at -225 odds presents a 2.7% edge, with simulations resulting in a probability of 71.9%.

Pacers ML (+100)

• Edge: 2.5%
• Probability: 52.5%
• Matchup: Bucks vs. Pacers (7:30PM ET, Tuesday)

Our model finds value on Pacers to win at +100 odds, supported by an edge of 2.5%.

Trail Blazers +5.5 (+100)

• Edge: 2.5%
• Probability: 52.5%
• Matchup: Pistons vs. Trail Blazers (10:00PM ET, Monday)

Our model has uncovered value on Trail Blazers +5.5 at +100 odds. A 52.5% probability produces a 2.5% edge, making this a strong play for today's NBA action.

NBA best bets summary: Monday, 12/22/2025

As of 9:31PM ET, here is our top NBA bet by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Pistons vs. Trail Blazers	Trail Blazers +5.5	+100 @ BetMGM	2.5%	52.5%
Bulls vs. Hawks	Hawks ML	-166 @ DraftKings	3.4%	65.8%
Wizards vs. Hornets	Hornets ML	-225 @ DraftKings	2.7%	71.9%
Bucks vs. Pacers	Pacers ML	+100 @ FanDuel	2.5%	52.5%
Pistons vs. Trail Blazers	Trail Blazers +5.5	+100 @ BetMGM	2.5%	52.5%

List of upcoming NBA games to bet on [12/22/2025]

• Pistons vs. Trail Blazers (10:00PM ET, Monday)
• Magic vs. Warriors (10:00PM ET, Monday)
• Wizards vs. Hornets (7:00PM ET, Tuesday)
• Nets vs. 76ers (7:00PM ET, Tuesday)
• Raptors vs. Heat (7:30PM ET, Tuesday)
• Pelicans vs. Cavaliers (7:30PM ET, Tuesday)
• Bucks vs. Pacers (7:30PM ET, Tuesday)
• Bulls vs. Hawks (7:30PM ET, Tuesday)
• Knicks vs. Timberwolves (8:00PM ET, Tuesday)
• Nuggets vs. Mavericks (8:00PM ET, Tuesday)
• Thunder vs. Spurs (8:30PM ET, Tuesday)
• Grizzlies vs. Jazz (9:00PM ET, Tuesday)
• Lakers vs. Suns (9:00PM ET, Tuesday)

Meet Dimebot, Dimers’ AI assistant

See how you can use Dimebot to ask questions, clarify data, and streamline your betting research.

Conclusion

Our NBA best bets are locked and loaded for December 22, 2025, featuring plays such as Trail Blazers +5.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate NBA insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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