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Monterrey vs. Puebla prediction, odds, Liga MX picks [4/21/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Monterrey vs Puebla predictions for Liga MX Tuesday.
Monterrey will square off with Puebla in the Liga MX playoffs at Estadio BBVA on Tuesday, commencing at 11:00 PM ET.
Based on the latest simulations, Dimers' advanced Liga MX model projects Monterrey as the most likely winner of the Monterrey vs. Puebla game.
This article offers an expanded analysis of Tuesday's match, including best bets and picks.
Monterrey vs. Puebla prediction: Who will win?
Using trusted machine learning and statistical analysis, we have simulated the result of Tuesday's Liga MX game between Monterrey and Puebla, forming part of our Liga MX predictions coverage.
Our leading predictive model suggests a 67.9% chance of Monterrey winning, a 14.0% chance for Puebla, and an 18.1% chance of a draw.
Monterrey vs. Puebla odds
We have researched the best Liga MX odds in America for this game, which are listed here:
| Market | Monterrey | Puebla | Draw |
|---|---|---|---|
| Moneyline | -230 | +600 | +370 |
All odds are correct at the time of publication and are subject to change.
Monterrey vs. Puebla picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Puebla | +600 |
According to our Liga MX best bets, the top play to make on this game is Puebla to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Monterrey vs. Puebla: Correct score and BTTS predictions
The top three most likely final scores, according to our model, are listed below, with a 2-0 Monterrey win being the most probable:
| Final Score | Probability |
|---|---|
| MNT 2-0 PUE | 10.1% |
| MNT 2-1 PUE | 9.7% |
| MNT 1-0 PUE | 8.6% |
When it comes to the both teams to score (BTTS) market, we project a 55.9% chance of both sides finding the net and a 44.1% chance that at least one doesn’t.
Monterrey vs. Puebla game-day updates and essential details
Tuesday's matchup between Monterrey and Puebla at Estadio BBVA is scheduled to start at 11:00 PM ET.
- Who: Monterrey vs. Puebla
- Date: Tuesday, April 21, 2026
- Time: 11:00 PM ET/8:00PM PT
- Venue: Estadio BBVA
Conclusion
According to our computer model, Monterrey has a 67.9% win probability on Tuesday, Puebla has a 14.0% win probability, and there is an 18.1% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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