Twins vs. Padres: MLB Prediction & Analysis

Our detailed prediction and analysis for the Twins vs. Padres MLB game on Friday, August 21, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
FINAL
MLB
FINAL
MLB sport icon
MLB
Twins
Connor Prielipp 3-6, 5.34 ERA
2
6
Petco Park
Padres
Randy Vásquez 8-6, 4.30 ERA
Petco Park
1 2 3 4 5 6 7 8 9 RHE
Twins
0 0 0 2 0 0 0 0 0 2 2 0
Padres
2 0 0 0 4 0 0 0 X 6 9 0
Live Probabilities
Win %
  • Twins
    0%
  • Padres
    100%
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Josh Bell strikes out on a foul tip.
Quick Box Score
Twins Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 L. Keaschall RF4010001.2500.500
2 B. Buxton CF4100001.0000.000
3 J. Bell DH3100001.0000.250
4 R. Jeffers C3000000.0000.000
5 K. Clemens 2B3012001.3331.333
6 R. Lewis 1B3000000.0000.000
7 T. Larnach LF3000001.0000.000
8 B. Lee 3B3000000.0000.000
9 K. Culpepper SS3000002.0000.000
Padres Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 F. Tatis RF4131000.7501.750
2 L. Rengifo DH4121000.5001.000
3 M. Machado 3B4121000.5001.000
4 T. France 1B11131201.0004.750
5 J. Merrill CF4000003.0000.000
6 X. Bogaerts SS4000002.0000.000
7 A. Hays LF4110002.2500.500
8 F. Fermin C3000001.0000.000
9 J. Cronenworth 2B1100021.0000.667

Twins vs. Padres: Detailed Breakdown

Matchup overview: MLB Friday

  • Teams: Minnesota Twins vs. San Diego Padres
  • Date: Friday, August 21, 2026
  • Time: 9:40PM ET
  • Venue: Petco Park

Current betting odds

  • Spread: Twins (+1.5, -182), Padres (-1.5, +178)
  • Moneyline: Twins +113, Padres -115
  • Total (Over/Under): 8.5 runs (+108/-111)

Dimers’ win probabilities

  • Twins: 50.8%
  • Padres: 49.2%

Dimers' predictive MLB model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Twins a win probability of 50.8%, while the Padres have a win probability of 49.2%.

Summary

According to our analysis, the Twins are more likely to beat the Padres in the MLB game at Petco Park on Friday. Discover the best run line, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Twins vs. Padres predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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