Sep 27, 2026
MLB picks today: Sunday's MLB best bets include Orioles vs. Yankees play [9/27/2026]
Read Article Diamondbacks vs. Padres prediction: Arizona favored to win Sunday's MLB matchup [9/27/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Dimers' simulation model projects a 52.9% win probability for the Diamondbacks at Petco Park.
The San Diego Padres and Arizona dbacks are scheduled to meet in MLB action at Petco Park on Sunday, starting at 3:10 PM ET.
Randy Vásquez (10-6, 4.01 ERA) will start for the Padres, pitting him against Michael Soroka (9-5, 3.31 ERA) for the Diamondbacks.
Dimers' proven MLB model gives the Diamondbacks a slight edge with a 52.9% win probability over the Padres.
This article offers a complete Diamondbacks vs. Padres prediction, including best bets and picks.
Diamondbacks vs. Padres prediction and odds
Using innovative machine learning and data analysis, we have re-simulated the result of Sunday's MLB matchup between the Diamondbacks and Padres, forming part of our MLB predictions coverage.
Our famous predictive model gives the Diamondbacks a 52.9% chance of defeating the Padres. According to our model, the Padres (+1.5) have a 59.5% chance of covering the run line, while the over/under total of 7.5 runs has a 58.5% chance of going over.
Latest betting odds
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Diamondbacks -1.5 (+140) / Padres +1.5 (-153)
- Moneyline: Diamondbacks -122, Padres +117
- Total: Over/Under 7.5 (-117/+106)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Padres +1.5 @ 60¢ via Novig
- Moneyline: Padres @ 46¢ via Novig
- Total: Over 7.5 @ 54¢ via Novig
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Sunday's MLB matchup between the Padres and Diamondbacks at Petco Park is scheduled to begin at 3:10 PM ET.
- Who: Arizona Diamondbacks vs. San Diego Padres
- Date: Sunday, September 27, 2026
- Time: 3:10 PM ET/12:10PM PT
- Venue: Petco Park
Conclusion
We predict the Diamondbacks, with a 52.9% win probability, will likely beat the Padres in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
This article's predictions and probabilities are generated by Dimers' proprietary MLB prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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