Pachuca vs. Cruz Azul prediction, odds, Liga MX picks [10/21/2026]

Using trusted machine learning and statistical analysis, we have re-simulated the result of Wednesday's Liga MX game between Pachuca and Cruz Azul, forming part of our Liga MX predictions coverage.

Our famous predictive model indicates a 32.0% chance of Pachuca winning, a 43.2% chance for Cruz Azul, and a 24.8% chance of a draw. Additionally, the 2.5-goal over/under has a 54.3% chance of going over., with a 57.4% probability that both teams score.

Latest betting odds

We have researched the best Liga MX odds in America for this game, which are listed here:

• Moneyline: Cruz Azul +130, Pachuca +185
• Total Goals: Over/Under 2.5 (-158/+124)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Cruz Azul @ +130 via DraftKings
• Total Goals: Under 2.5 @ +124 via FanDuel

According to our Liga MX best bets, the top play to make on this game is Under 2.5 total goals.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Correct score and BTTS projections

Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:

• Pachuca 1-1 Cruz Azul (11.6% probability)
• Pachuca 1-2 Cruz Azul (9%)
• Pachuca 0-1 Cruz Azul (8.9%)

When it comes to the both teams to score (BTTS) market, we project a 57.4% chance of both sides finding the net and a 42.6% chance that at least one doesn’t.

These predictions are based on each team's average score according to our machine learning model, meaning the most likely correct score can differ from our predicted winner.

Game info & kickoff details

Wednesday's Liga MX game between Pachuca and Cruz Azul at Estadio Miguel Hidalgo is scheduled to begin at 11:00 PM ET.

• Who: Pachuca vs. Cruz Azul
• Date: Wednesday, October 21, 2026
• Time: 11:00 PM ET/8:00 PM PT
• Venue: Estadio Miguel Hidalgo

Conclusion

According to our computer model, Pachuca has a 32.0% win probability on Wednesday, Cruz Azul has a 43.2% win probability, and there is a 24.8% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary Liga MX prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.