Wyoming vs. North Dakota State prediction favors North Dakota State to win in college football Week 5 [2026]

Using powerful machine learning and data, we have re-simulated the outcome of Wyoming vs. North Dakota State, forming part of our college football predictions coverage.

Our famous predictive model gives North Dakota State a 90.6% chance of defeating Wyoming. Our predicted final score has North Dakota State winning 30-14. According to our model, North Dakota State (-16.5) has a 50.6% chance of covering the spread, while the 43.5-point over/under has a 54.8% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Wyoming +16.5 (+100) / North Dakota State -16.5 (-112)
• Moneyline: Wyoming +740, North Dakota State -1000
• Total: Over/Under 43.5 (-120/-105)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Wyoming +16.5 @ +100 via bet365
• Moneyline: North Dakota State @ -1000 via DraftKings
• Total: Over 43.5 @ -120 via BetRivers

According to our best college football bets, the top play to make on this game is Over 43.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between North Dakota State and Wyoming at Gate City Bank Field at the Fargodome is scheduled to commence at 3:30 PM ET.

• Who: Wyoming vs. North Dakota State
• Date: Saturday, October 3, 2026
• Time: 3:30 PM ET/12:30PM PT
• Venue: Gate City Bank Field at the Fargodome

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Conclusion

We predict North Dakota State, with a 90.6% win probability, will likely beat Wyoming in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.