Ole Miss vs. Oklahoma prediction favors Oklahoma to win in college football Week 11 [2026]

Using powerful machine learning and data, we have re-simulated the outcome of Ole Miss vs. Oklahoma, forming part of our college football predictions coverage.

Our famous predictive model currently gives Oklahoma a 57.1% chance of defeating Mississippi. Our predicted final score has Oklahoma winning 26-23. According to our model, Oklahoma (-2.5) has a 50.6% chance of covering the spread, while the over/under total of 48.5 points has a 52.1% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Ole Miss +2.5 (+104) / Oklahoma -2.5 (-108)
• Moneyline: Ole Miss +125, Oklahoma -127
• Total: Over/Under 48.5 (-104/+100)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Mississippi +2.5 @ 49¢ via Novig
• Moneyline: Oklahoma @ 56¢ via Novig
• Total: Over 48.5 @ 51¢ via Novig

According to our college football best bets, the top play to make on this game is Over 48.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Sunday's college football action between Oklahoma and Ole Miss at Gaylord Family Oklahoma Memorial Stadium is scheduled to commence at 1:00 PM ET.

• Who: Mississippi vs. Oklahoma
• Date: Sunday, November 15, 2026
• Time: 1:00 PM ET/10:00 AM PT
• Venue: Gaylord Family Oklahoma Memorial Stadium

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Conclusion

We predict Oklahoma, with a 57.1% win probability, will likely beat Mississippi in Sunday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary college football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.