Lehigh vs. Pennsylvania prediction: Why Lehigh is favored to win in college football Week 4 [2026]

Using trusted machine learning and statistical analysis, we have re-simulated the outcome of Lehigh vs. Pennsylvania, forming part of our college football predictions coverage.

Our independent predictive model currently gives Lehigh a 78.2% chance of defeating Pennsylvania. Our predicted final score has Lehigh winning 29-18. According to our model, Pennsylvania (+12.5) has a 52.8% chance of covering the spread, while the over/under total of 46.5 points has a 52.9% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Lehigh -12.5 (-104) / Pennsylvania +12.5 (-120)
• Moneyline: Lehigh -450, Pennsylvania +337
• Total: Over/Under 46.5 (-111/-111)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Pennsylvania +12.5 @ -120 via bet365
• Moneyline: Pennsylvania @ +337 via DraftKings
• Total: Over 46.5 @ -111 via DraftKings

According to our college football best bets, the top play to make on this game is Over 46.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between Pennsylvania and Lehigh at Franklin Field is scheduled to commence at 1:00 PM ET.

• Who: Lehigh vs. Pennsylvania
• Date: Saturday, September 26, 2026
• Time: 1:00 PM ET/10:00AM PT
• Venue: Franklin Field

College football Week 4 promos

Make the most of Dimers' Lehigh vs. Pennsylvania predictions by exploring the Bet365 Sportsbook offer below:

Conclusion

We predict Lehigh, with a 78.2% win probability, will likely beat Pennsylvania in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.