Bears vs. Bills: NFL Week 15 Prediction, Picks & Odds
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- Bears
- Bills
Bears vs. Bills: Detailed Breakdown
Matchup overview: NFL Week 15
- Teams: Chicago Bears vs. Buffalo Bills
- Date: Saturday, December 19, 2026
- Time: 8:20PM ET
- Venue: Highmark Stadium
Current betting odds
- Spread: Bears (+4, -115), Bills (-4, -115)
- Moneyline: Bears +160, Bills -200
- Total (Over/Under): 51.5 points (-115/-115)
Dimers’ win probabilities
- Bears: 37.3%
- Bills: 62.7%
These probabilities come from two machine learning models that assess more than 100 data points for each NFL matchup, combining their outputs to project all our major betting markets.
Projected final score
Our predicted final score for this NFL matchup is Bears 23-27 Bills.
This prediction draws on each team's scoring trends and player stats, weighed across both of our data models
Our Prediction: Who Wins?
The numbers give the Bears a win probability of 37.3%, while the Bills have a win probability of 62.7%.
Summary
The Bears face off against the Bills in the NFL at Highmark Stadium on Saturday, December 19, 2026.
Our Bears vs. Bills predictions, built on real-time data and matchup-specific modeling, help guide your decisions. Remember to bet responsibly and within your financial limits.
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For further insights, explore our expert NFL predictions and the best NFL bets today, while our in-depth analysis includes NFL props, NFL futures, NFL odds, and the latest NFL news.