Titans vs. Broncos prediction: Denver favored to win in NFL Week 1, 2025

The Denver Broncos will take on the Tennessee Titans in NFL Week 1 action at Empower Field at Mile High on Sunday, commencing at 4:05PM ET.

Based on updated simulation results, Dimers' advanced NFL model projects the Broncos as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Titans-Broncos game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Broncos with a win probability of 79%, while the Titans have 21%."

This updated Titans vs. Broncos betting preview builds on my Titans vs. Broncos prediction that was published earlier in the week.

For expanded analysis of today’s game, including the predicted score, best bets and player prop picks, visit our interactive Titans vs. Broncos predictions page.

Titans vs. Broncos Predictions

Since our Titans-Broncos predictions earlier in the week, we have simulated the outcome of Sunday's NFL game between the Titans and Broncos 10,000 times as part of our NFL predictions coverage.

Our independent predictive model gives the Broncos a 79% chance of defeating the Titans in Week 1 of the NFL season. Our predicted final score has the Broncos winning 25-17.

According to our model, the bookies have got it right, and the Titans and Broncos each have a 50% chance of covering the spread, while the 42.5-point over/under also has an equal 50-50 chance of hitting.

Titans vs. Broncos odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type	Titans	Broncos
Spread	+8.5 (-105)	-8.5 (-115)
Moneyline	+385	-455
Total	o42.5 (-110)	u42.5 (-108)

All odds are correct at the time of publication and are subject to change.

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Titans vs. Broncos picks and best bets

Our model's biggest edge in today's Titans vs. Broncos matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best NFL picks and NFL best bets for every game throughout the season, with today's best NFL bets populating now.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Titans vs. Broncos TD scorers

Who will score the first touchdown in Titans vs. Broncos?

According to our list of touchdown scorer predictions for Week 1, Tennessee's Tony Pollard is most likely to score the first touchdown in Titans vs. Broncos.

Our projections give Pollard a 10.4% chance of scoring the first TD at Empower Field at Mile High, while the Titans running back is a 37.4% chance of registering an anytime touchdown.

First touchdown scorer predictions

Tennessee Titans

Player	First TD Probability
Tony Pollard (RB)	10.4%
Calvin Ridley (WR)	7.0%
Tyler Lockett (WR)	3.9%

Denver Broncos

Player	First TD Probability
J.K. Dobbins (RB)	9.3%
Courtland Sutton (WR)	9.1%
RJ Harvey (RB)	9.1%

Anytime touchdown scorer predictions

Tennessee Titans

Player	Anytime TD Probability
Tony Pollard (RB)	37.4%
Calvin Ridley (WR)	27.0%
Tyler Lockett (WR)	16.0%

Denver Broncos

Player	Anytime TD Probability
J.K. Dobbins (RB)	36.0%
Courtland Sutton (WR)	35.5%
RJ Harvey (RB)	35.4%

For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 1 touchdown scorer predictions

Titans vs Broncos player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Titans and Broncos. For more, check out today's highest-probability NFL prop bets.

Already a Dimers Pro member? Head to our Titans-Broncos page now to access every player prop projection.

Titans vs. Broncos quarterbacks

Of the starting quarterbacks, the Titans' Cam Ward is projected to throw for fewer yards than the Broncos' Bo Nix.

Titans rushing

Tony Pollard, Cam Ward and Julius Chestnut are projected to be the leading rushers for the Titans.

Player	Position
Tony Pollard	RB
Cam Ward	QB
Julius Chestnut	RB

Broncos rushing

RJ Harvey, J.K. Dobbins and Bo Nix are expected to lead the Broncos in rushing yards.

Player	Position
RJ Harvey	RB
J.K. Dobbins	RB
Bo Nix	QB

Titans receiving

Calvin Ridley, Chig Okonkwo, Elic Ayomanor, Tyler Lockett and Tony Pollard are projected to top the receiving yards for the Titans.

Player	Position
Calvin Ridley	WR
Chig Okonkwo	TE
Elic Ayomanor	WR
Tyler Lockett	WR
Tony Pollard	RB

Broncos receiving

Courtland Sutton, Marvin Mims, Evan Engram, Troy Franklin and RJ Harvey are projected to lead the Broncos in receiving yards.

Player	Position
Courtland Sutton	WR
Marvin Mims	WR
Evan Engram	TE
Troy Franklin	WR
RJ Harvey	RB

Titans vs. Broncos game-day updates and essential details

The NFL Week 1 action between the Broncos and Titans at Empower Field at Mile High is scheduled to begin at 4:05PM ET.

• Who: Tennessee Titans vs. Denver Broncos
• Date: Sunday, September 7, 2025
• Time: 4:05PM ET/1:05PM PT
• Venue: Empower Field at Mile High

Dimers.com's in-depth preview of Sunday's Titans vs. Broncos matchup includes our prediction, picks and the latest betting odds.

Before making any Titans vs. Broncos picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Broncos, with a 79% win probability, will likely beat the Titans in Week 1 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Titans vs. Broncos insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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