NFL Week 2 2021: Picks, Predictions and Odds

NFL Week 2 2021: Picks, Predictions and Odds

Another Super Sunday is here and we are locked and loaded with our three best plays for today's action plus a 'lil parlay action for you.

The 2021 NFL season continues on Sunday September 19, 2021, and, as always, Dimers.com has simulated every Week 2 game to determine where the value lies for football bettors across the United States.

With NFL betting picks, probabilities, odds and predicted scores featured each and every week at Dimers, check out our top plays for Sunday's NFL games.

MORE: DimersBOT's most likely TD scorers

Today's NFL best bets and odds are proudly brought to you by TwinSpires Sportsbook.‍

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Free NFL Picks For Sunday September 19, 2021

Rams vs. Colts

BET: Total points UNDER 48 with TwinSpires (-105)

📈 3.2% edge on the sportsbooks' odds

The Rams were impressive last week against the Bears, on both the offensive and defensive sides of the field. Whilst we expect them to win again this week, there's not enough value there so we're instead tackling the total points.

The LA defense is looking like it will be one of the strongest in the league again this season and they should have no trouble keeping the Colts to a low score, with the Under following suit.

MORE: Rams vs. Colts predictions and picks


Titans vs. Seahawks

BET: Titans +6.5 with TwinSpires (-110)

📈 57% probability

Derrick Henry and the Titans were one of the most disappointing teams of Week 1 and they now come into this game as 6.5-point underdogs.

Although the Seahawks looked good last week, we're taking Tennessee to at least keep this one close, with the team set to come out firing.

MORE: Titans vs. Seahawks predictions and picks


Chiefs vs. Ravens

BET: Chiefs -3.5 with TwinSpires (-110)

📈 56% probability

We should be set for an awesome game here, but there's also something that stands out to us: Patrick Mahomes has never lost to Lamar Jackson. 

So of course, you could take KC at the moneyline, but with DimersBOT giving them a 57% chance of covering, the value is definitely there for them at the spread. Find out which 6 players it likes to score a touchdown

MORE: Chiefs vs. Ravens predictions and picks

Your game not here? Find out who we're betting on for every NFL game on Sunday via our NFL Bet Hub, where we deliver you NFL predictions and suggested bets.


NFL Parlay For Sunday September 19, 2021

🔥 Rams/Colts u48 points
🔥 Titans +6.5
🔥 Chiefs -3.5

Parlay Odds +611


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TwinSpires not available in your state? We recommend Caesars Sportsbook as the next best option. Get a RISK-FREE BET up to $5,000 + a free NFL Jersey when you join with Dimers.


Full NFL Schedule Week 2 2021

Thursday September 16, 2021

Sunday September 19, 2021

Monday September 20, 2021


All 2021 NFL Week 2 times are subject to change.

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For articles with several contributors, we use this author profile. Since we want our readers to hear from all of our experts, we use it frequently. This profile is also used for new sportsbook promos and offers, or our favorite bets in a particular sport on any given day. Our contributors' level of experience spans all sports and bet types. We hope we have you covered, no matter what you're betting on.

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