Knicks vs. Timberwolves prediction: Minnesota to win, Anthony Edwards projected for big game in Tuesday's NBA matchup [12/23/2025]

The Minnesota Timberwolves will square off with the New York Knicks in NBA action at Target Center on Tuesday, beginning at 8:00 PM ET.

Based on updated simulation results and today’s injury reports, Dimers' proven NBA model predicts the Timberwolves as the most likely winner of the Knicks vs. Timberwolves game.

This prediction follows the latest NBA Injury Report, which suggests the Timberwolves lineup will feature players like Anthony Edwards, Julius Randle and Donte DiVincenzo, while the Knicks will be led by Karl-Anthony Towns, Mikal Bridges and Jordan Clarkson.

This article offers an expanded analysis of Tuesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Knicks vs. Wolves prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the result of Tuesday's NBA matchup between the Knicks and Timberwolves 10,000 times as part of our NBA predictions coverage.

Our independent predictive model gives the Timberwolves a 72% chance of defeating the Knicks. Our predicted final score has the Timberwolves winning 117-111.

According to our model, the Knicks (+7.5) have a 53% chance of covering the spread, while the over/under total of 229.5 points has a 51% chance of staying under.

Knicks vs. Timberwolves odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type	Knicks	Timberwolves
Spread	+7.5 (-110)	-7.5 (-105)
Moneyline	+225	-270
Total	o229.5 (-114)	u229.5 (-105)

All odds are correct at the time of publication and are subject to change.

Knicks vs. Timberwolves picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Knicks +7.5	-110
Moneyline	Timberwolves	-270
Total	Under 229.5	-105

According to our best NBA bets for Tuesday, the top play to make on this game is Knicks +7.5 at the spread.

Knicks vs. Timberwolves player props

NBA prop bets are an enjoyable way to wager on Tuesday's New York vs. Minnesota matchup without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Target Center.

Karl-Anthony Towns is expected to lead the Knicks with 23 points, 11 rebounds and 3 assists, while Anthony Edwards is projected to have 28 points, 6 rebounds and 5 assists for the Timberwolves.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Knicks prediction

Our model's projected player stats for the Knicks are:

Player	PTS	REB	AST	3PM	DFS
K. Towns	23	11	3	2	45
Mikal Bridges	19	4	4	2	38
Jordan Clarkson	14	3	3	2	25
Josh Hart	13	8	5	1	36
Tyler Kolek	11	3	7	1	30

Timberwolves prediction

Projected points, rebounds, assists and three-pointers made for the Timberwolves:

Player	PTS	REB	AST	3PM	DFS
Anthony Edwards	28	6	5	3	49
Julius Randle	21	6	5	2	41
D. DiVincenzo	14	4	4	3	31
Naz Reid	13	6	2	3	30
Bones Hyland	11	2	3	2	24

Knicks vs. Wolves game-day updates and essential details

Tuesday's matchup between the Timberwolves and Knicks at Target Center is scheduled to start at 8:00 PM ET.

• Who: New York Knicks vs. Minnesota Timberwolves
• Date: Tuesday, December 23, 2025
• Time: 8:00 PM ET/5:00PM PT
• Venue: Target Center

Conclusion

We predict the Timberwolves, with a 72% win probability, will likely beat the Knicks on Tuesday, with Anthony Edwards projected for a game-high 49 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Knicks vs. Timberwolves insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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