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Knicks vs. Timberwolves prediction: Minnesota to win, Anthony Edwards projected for big game in Tuesday's NBA matchup [12/23/2025]

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Written by Dave Garofolo

Get New York Knicks vs Minnesota Timberwolves predictions for NBA Tuesday.

New York Knicks-Minnesota Timberwolves Predictions and Game Preview.
New York Knicks vs. Minnesota Timberwolves NBA prediction for Tuesday, December 23, 2025.

The Minnesota Timberwolves and New York Knicks will meet in NBA action at Target Center on Tuesday, starting at 8:00 PM ET.

Based on the latest simulations and today’s injury updates, Dimers' proven NBA model projects the Timberwolves as the most likely winner of the Knicks vs. Timberwolves game.

This prediction follows the latest NBA Injury Report, which suggests the Timberwolves lineup will feature players like Anthony Edwards, Julius Randle and Jaden McDaniels, while the Knicks will be led by Karl-Anthony Towns, Mikal Bridges and Jordan Clarkson.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Knicks vs. Wolves prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Tuesday's NBA game between the Knicks and Timberwolves 10,000 times as part of our NBA predictions coverage.

Our leading predictive model currently gives the Timberwolves a 73% chance of defeating the Knicks. Our predicted final score has the Timberwolves winning 117-110.

According to our model, the Knicks (+7.5) have a 53% chance of covering the spread, while the over/under total of 227.5 points has a 51% chance of going over.

 

Knicks vs. Timberwolves odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Knicks Timberwolves
Spread +7.5 (-108) -7.5 (-112)
Moneyline +245 -290
Total o227.5 (-112) u227.5 (-108)

All odds are correct at the time of publication and are subject to change.

Knicks vs. Timberwolves picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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