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Pelicans vs. Cavaliers prediction: Cleveland to win, Donovan Mitchell projected for big game in Tuesday's NBA matchup [12/23/2025]

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Written by Ryan Leaver

Get New Orleans Pelicans vs Cleveland Cavaliers predictions for NBA Tuesday.

New Orleans Pelicans-Cleveland Cavaliers Predictions and Game Preview.
New Orleans Pelicans vs. Cleveland Cavaliers NBA prediction for Tuesday, December 23, 2025.

The Cleveland Cavaliers and New Orleans Pelicans will lock horns in NBA action at Rocket Arena on Tuesday, with tipoff at 7:30 PM ET.

Based on the latest simulation results and today’s injury news, Dimers' advanced NBA model predicts the Cavaliers as the most likely winner of the Pelicans vs. Cavaliers game.

This prediction follows the latest NBA Injury Report, which suggests the Cavaliers lineup will feature players like Donovan Mitchell, Darius Garland and De'Andre Hunter, while the Pelicans will rely on Trey Murphy, Zion Williamson and Jordan Poole.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Pelicans vs. Cavs prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the result of Tuesday's NBA matchup between the Pelicans and Cavaliers 10,000 times as part of our NBA predictions coverage.

Our independent predictive model currently gives the Cavaliers a 76% chance of beating the Pelicans. Our predicted final score has the Cavaliers winning 125-117.

According to our model, the Pelicans (+9.5) have a 54% chance of covering the spread, while the over/under total of 244.5 points has a 54% chance of staying under.

 

Pelicans vs. Cavaliers odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Pelicans Cavaliers
Spread +9.5 (-110) -9.5 (-110)
Moneyline +330 -380
Total o244.5 (-112) u244.5 (-105)

All odds are correct at the time of publication and are subject to change.

Pelicans vs. Cavaliers picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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