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Clippers vs. Trail Blazers prediction: Why Clippers are favored to win Friday's NBA game [12/26/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Los Angeles Clippers vs Portland Trail Blazers predictions for NBA Friday.
The Portland Trail Blazers will square off with the Los Angeles Clippers in NBA action at Moda Center on Friday, starting at 10:00 PM ET.
Based on updated simulation results and today’s injury updates, Dimers' proven NBA model predicts the Clippers as the most likely winner of the Clippers vs. Trail Blazers game.
This prediction follows the latest NBA Injury Report, which suggests the Trail Blazers lineup will feature stars like Deni Avdija, Shaedon Sharpe and Toumani Camara, while the Clippers will be led by Kawhi Leonard, James Harden and John Collins.
This article offers a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Clippers vs. Blazers prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the outcome of Friday's NBA matchup between the Clippers and Trail Blazers 10,000 times as part of our NBA predictions coverage.
Our famous predictive model gives the Clippers a 58% chance of defeating the Trail Blazers. Our predicted final score has the Clippers winning 114-112.
According to our model, the Trail Blazers (+1) have a 51% chance of covering the spread, while the 226.5-point over/under has an equal 50-50 chance of hitting.
Clippers vs. Trail Blazers odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Clippers | Trail Blazers |
|---|---|---|
| Spread | -1 (-114) | +1 (-106) |
| Moneyline | -120 | +105 |
| Total | o226.5 (-110) | u226.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Clippers vs. Trail Blazers picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Trail Blazers +1 | -106 |
| Moneyline | Clippers | -120 |
| Total | Under 226.5 | -105 |
According to our best NBA bets for Friday, the top play to make on this game is Clippers to win.
Clippers vs. Trail Blazers player props
Betting on Clippers vs. Trail Blazers NBA prop bets? We have crunched the numbers to project how each team's leading players will perform at Moda Center.
Kawhi Leonard is expected to lead the Clippers with 27 points, 7 rebounds and 4 assists, while Deni Avdija is projected to have 27 points, 8 rebounds and 7 assists for the Trail Blazers.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
Clippers prediction
Our model's projected player stats for the Clippers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Kawhi Leonard | 27 | 7 | 4 | 2 | 50 |
| James Harden | 24 | 5 | 9 | 3 | 52 |
| John Collins | 15 | 6 | 1 | 1 | 30 |
| Brook Lopez | 11 | 4 | 2 | 2 | 25 |
| Kris Dunn | 9 | 3 | 3 | 1 | 24 |
Trail Blazers prediction
Projected points, rebounds, assists and three-pointers made for the Trail Blazers:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Deni Avdija | 27 | 8 | 7 | 2 | 53 |
| Shaedon Sharpe | 24 | 5 | 3 | 2 | 40 |
| Toumani Camara | 13 | 5 | 3 | 2 | 28 |
| Donovan Clingan | 11 | 11 | 2 | 1 | 34 |
| Caleb Love | 8 | 3 | 2 | 1 | 18 |
Clippers vs. Blazers game-day updates and essential details
Friday's matchup between the Trail Blazers and Clippers at Moda Center is scheduled to commence at 10:00 PM ET.
- Who: Los Angeles Clippers vs. Portland Trail Blazers
- Date: Friday, December 26, 2025
- Time: 10:00 PM ET/7:00PM PT
- Venue: Moda Center
Conclusion
We predict the Clippers, with a 58% win probability, will likely beat the Trail Blazers on Friday, with Deni Avdija projected for a game-high 53 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Clippers vs. Trail Blazers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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