Houston Texans vs. Indianapolis Colts updated prediction featuring Woody Marks, Jonathan Taylor [Week 13, 2025]

Dimers' latest NFL predictions are live for Indianapolis Colts vs. Houston Texans in Week 13, with our model giving the Colts a 67% of winning.

As Sunday approaches, both teams have updated their injury reports. A few lineup decisions are still up in the air, and those could shape how each side approaches this AFC South clash.

Since our early Colts-Texans predictions, we’ve updated the win probabilities, score projections, and TD odds for Woody Marks, Jonathan Taylor, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—check out our Texans vs. Colts page.

What's changed? Houston vs. Indianapolis updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Texans vs. Colts matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Texans 33%, Colts 67%
• Predicted Final Score: Texans 20-24 Colts
• Spread: Texans (+4) 49%, Colts (-4) 51%
• Total Points (44.5): Over 50%, Under 50%

As of November 27, 2025, these Texans-Colts numbers reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 13 highlight the top candidates to find the end zone in Texans-Colts on Sunday:

Houston Texans

• Woody Marks: 40.3% probability
• Nico Collins: 39.5% probability
• Jayden Higgins: 26.2% probability

Indianapolis Colts

• Jonathan Taylor: 68.7% probability
• Michael Pittman: 28.6% probability
• Tyler Warren: 27.3% probability

Texans vs. Colts latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Texans +4 (-110), Colts -4 (-110)
• Moneyline: Texans +180, Colts -210
• Total: Over/Under 44.5 (-110/-105)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Texans vs. Colts Week 13 details

The NFL Week 13 game between the Colts and Texans at Lucas Oil Stadium is scheduled for November 30, 2025.

• Who: Houston Texans vs. Indianapolis Colts
• Date: Sunday, November 30, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Lucas Oil Stadium

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Conclusion

We predict the Colts, with a 67% win probability, will likely beat the Texans in Week 13 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Texans vs. Colts matchup, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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