Cavaliers vs. Wizards prediction: Cleveland to win, Donovan Mitchell projected for big game in Friday's NBA matchup [12/12/2025]

The Washington Wizards will face the favored Cleveland Cavaliers in NBA action at Capital One Arena on Friday, commencing at 7:00PM ET.

Based on the latest simulation results and today’s injury reports, Dimers' advanced NBA model predicts the Cavaliers as the most likely winner of the Cavaliers vs. Wizards game.

This prediction follows the latest NBA Injury Report, which suggests the Wizards lineup will feature stars like CJ McCollum, Kyshawn George and Marvin Bagley, while the Cavaliers will rely on Donovan Mitchell, Evan Mobley and Darius Garland.

This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Cavs vs. Wizards prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Friday's NBA matchup between the Cavaliers and Wizards 10,000 times as part of our NBA predictions coverage.

Our leading predictive model gives the Cavaliers an 89% chance of defeating the Wizards. Our predicted final score has the Cavaliers winning 128-114.

According to our model, the Wizards (+16) have a 57% chance of covering the spread, while the 245.5-point over/under has a 54% chance of staying under.

Cavaliers vs. Wizards odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type	Cavaliers	Wizards
Spread	-16 (-110)	+16 (-110)
Moneyline	-1350	+830
Total	o245.5 (-110)	u245.5 (-105)

All odds are correct at the time of publication and are subject to change.

Cavaliers vs. Wizards picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Wizards +16	-110
Moneyline	Wizards	+830
Total	Under 245.5	-105

According to our best NBA bets for Friday, the top play to make on this game is Wizards +16 at the spread.

Cavaliers vs. Wizards player props

Betting on Cleveland vs. Washington NBA prop bets? We use the best information available to project how each team's leading players will perform at Capital One Arena.

Donovan Mitchell is expected to lead the Cavaliers with 30 points, 5 rebounds and 6 assists, while CJ McCollum is projected to have 20 points, 3 rebounds and 4 assists for the Wizards.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Cavaliers prediction

Our model's projected player stats for the Cavaliers are:

Player	PTS	REB	AST	3PM	DFS
D. Mitchell	30	5	6	4	52
Evan Mobley	21	10	4	2	48
Darius Garland	20	3	7	3	39
De'Andre Hunter	16	5	2	2	30
Jaylon Tyson	14	7	3	2	32

Wizards prediction

Projected points, rebounds, assists and three-pointers made for the Wizards:

Player	PTS	REB	AST	3PM	DFS
CJ McCollum	20	3	4	3	35
Kyshawn George	15	6	5	2	35
Marvin Bagley	13	7	2	0	30
T. Vukcevic	12	5	1	2	25
J. Champagnie	11	7	1	1	27

Cavs vs. Wizards game-day updates and essential details

Friday's matchup between the Wizards and Cavaliers at Capital One Arena is scheduled to commence at 7:00PM ET.

• Who: Cleveland Cavaliers vs. Washington Wizards
• Date: Friday, December 12, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Capital One Arena

Conclusion

We predict the Cavaliers, with an 89% win probability, will likely beat the Wizards on Friday, with Donovan Mitchell projected for a game-high 52 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Cavaliers vs. Wizards insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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