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Cavaliers vs. 76ers prediction: Philadelphia to win, Donovan Mitchell projected for big game in Wednesday's NBA matchup [1/14/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Cleveland Cavaliers vs Philadelphia 76ers predictions for NBA Wednesday.
The Philadelphia 76ers and Cleveland Cavaliers are scheduled to meet in NBA action at Xfinity Mobile Arena on Wednesday, with tipoff at 7:00 PM ET.
Based on updated simulations and today’s injury updates, Dimers' proven NBA model gives the 76ers a slight edge with a 54% win probability over the Cavaliers.
This prediction follows the latest NBA Injury Report, which suggests the 76ers lineup will feature players like Tyrese Maxey, Joel Embiid and Paul George, while the Cavaliers will rely on Donovan Mitchell, Darius Garland and Evan Mobley.
This article offers an expanded analysis of Wednesday's Cavaliers vs. 76ers matchup, including an expanded look at the predicted score, best bets and player prop picks.
Sixers vs. Sixers prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of Wednesday's NBA matchup between the Cavaliers and 76ers 10,000 times as part of our NBA predictions coverage.
Our independent predictive model gives the 76ers a 54% chance of defeating the Cavaliers. Our predicted final score has the 76ers winning 117-116.
According to our model, the Cavaliers (-1.5) have a 52% chance of covering the spread, while the over/under total of 236.5 points has a 55% chance of staying under.
Cavaliers vs. 76ers odds
We have researched the best NBA odds in America for this game, which are listed here:
| Bet Type | Cavaliers | 76ers |
|---|---|---|
| Spread | -1.5 (+100) | +1.5 (-120) |
| Moneyline | -102 | -108 |
| Total | o236.5 (-110) | u236.5 (-106) |
All odds are correct at the time of publication and are subject to change.
Cavaliers vs. 76ers picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Cavaliers -1.5 | +100 |
| Moneyline | 76ers | -108 |
| Total | Under 236.5 | -106 |
According to our best NBA bets for Wednesday, the top play to make on this game is 76ers to win.
Cavaliers vs. 76ers player props
NBA player props are a great way to wager on Wednesday's Cavaliers vs. 76ers game without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Xfinity Mobile Arena.
Donovan Mitchell is expected to lead the Cavaliers with 28 points, 5 rebounds and 6 assists, while Tyrese Maxey is projected to have 26 points, 4 rebounds and 7 assists for the 76ers.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
Cavaliers prediction
Our model's projected player stats for the Cavaliers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| D. Mitchell | 28 | 5 | 6 | 3 | 49 |
| Darius Garland | 18 | 3 | 7 | 2 | 37 |
| Evan Mobley | 18 | 9 | 4 | 2 | 41 |
| Jarrett Allen | 14 | 9 | 2 | 0 | 33 |
| Jaylon Tyson | 12 | 5 | 2 | 2 | 25 |
76ers prediction
Projected points, rebounds, assists and three-pointers made for the 76ers:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Tyrese Maxey | 26 | 4 | 7 | 3 | 48 |
| Joel Embiid | 25 | 9 | 4 | 2 | 49 |
| Paul George | 16 | 5 | 4 | 3 | 34 |
| VJ Edgecombe | 15 | 5 | 5 | 2 | 35 |
| Quentin Grimes | 12 | 3 | 3 | 2 | 26 |
Cavs vs. Sixers game-day updates and essential details
Wednesday's action between the 76ers and Cavaliers at Xfinity Mobile Arena is scheduled to commence at 7:00 PM ET.
- Who: Cleveland Cavaliers vs. Philadelphia 76ers
- Date: Wednesday, January 14, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: Xfinity Mobile Arena
Conclusion
We predict the 76ers, with a 54% win probability, will likely beat the Cavaliers on Wednesday, with Donovan Mitchell projected for a game-high 49 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Cavaliers vs. 76ers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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