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Cavaliers vs. Pacers prediction: Why Cleveland is favored to win Tuesday's NBA matchup [1/6/2026]

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Written by Ryan Leaver

Get Cleveland Cavaliers vs Indiana Pacers predictions for NBA Tuesday.

Cleveland Cavaliers-Indiana Pacers Predictions and Game Preview.
Cleveland Cavaliers vs. Indiana Pacers NBA prediction for Tuesday, January 6, 2026.

NBA action continues on Tuesday at 7:00 PM ET as the favored Cleveland Cavaliers square off with the Indiana Pacers at Gainbridge Fieldhouse.

Based on updated simulations and today’s injury reports, Dimers' advanced NBA model predicts the Cavaliers as the most likely winner of the Cavaliers vs. Pacers game.

This prediction follows the latest NBA Injury Report, which suggests the Pacers lineup will feature stars like Pascal Siakam, Andrew Nembhard and Aaron Nesmith, while the Cavaliers will be led by Darius Garland, Evan Mobley and De'Andre Hunter.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Cavs vs. Pacers prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Tuesday's NBA game between the Cavaliers and Pacers 10,000 times as part of our NBA predictions coverage.

Our famous predictive model currently gives the Cavaliers a 69% chance of beating the Pacers. Our predicted final score has the Cavaliers winning 120-114.

According to our model, the Pacers (+6.5) have a 53% chance of covering the spread, while the over/under total of 236.5 points has a 53% chance of staying under.

 

Cavaliers vs. Pacers odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Cavaliers Pacers
Spread -6.5 (-108) +6.5 (-108)
Moneyline -225 +200
Total o236.5 (-112) u236.5 (-108)

All odds are correct at the time of publication and are subject to change.

Cavaliers vs. Pacers picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Pacers +6.5 -108
Moneyline Cavaliers -225
Total Under 236.5 -108

According to our best NBA bets for Tuesday, the top play to make on this game is Under 236.5 total points.

 

Cavaliers vs. Pacers player props

Looking for Cleveland vs. Indiana NBA player props? We use the best information available to project how each team's leading players will perform at Gainbridge Fieldhouse.

Darius Garland is expected to lead the Cavaliers with 22 points, 3 rebounds and 7 assists, while Pascal Siakam is projected to have 25 points, 7 rebounds and 5 assists for the Pacers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Cavaliers prediction

Our model's projected player stats for the Cavaliers are:

Player PTS REB AST 3PM DFS
Darius Garland 22 3 7 2 42
Evan Mobley 19 9 4 1 43
De'Andre Hunter 15 4 2 2 26
Jarrett Allen 14 9 2 0 32
Jaylon Tyson 13 6 2 2 28

Pacers prediction

Projected points, rebounds, assists and three-pointers made for the Pacers:

Player PTS REB AST 3PM DFS
Pascal Siakam 25 7 5 2 46
Andrew Nembhard 18 3 7 2 36
Aaron Nesmith 17 5 2 3 32
T.J. McConnell 11 3 5 0 27
Micah Potter 8 7 2 1 24

Cavs vs. Pacers game-day updates and essential details

Tuesday's matchup between the Pacers and Cavaliers at Gainbridge Fieldhouse is scheduled to commence at 7:00 PM ET.

Conclusion

We predict the Cavaliers, with a 69% win probability, will likely beat the Pacers on Tuesday, with Pascal Siakam projected for a game-high 46 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Cavaliers vs. Pacers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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