Guardians vs. Phillies Prediction, Picks and Odds

Our detailed prediction and analysis for the Guardians vs. Phillies MLB game on May 22, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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Guardians
Gavin Williams 6-3, 3.67 ERA
1
0
May 22, 6:40 PM ET Citizens Bank Park
Phillies
Cristopher Sánchez 5-2, 1.82 ERA
May 22, 6:40 PM ET Citizens Bank Park
1 2 3 4 5 6 7 8 9 RHE
Guardians
0 0 0 0 0 0 0 0 1 1 6 1
Phillies
0 0 0 0 0 0 0 0 0 0 4 0
Live Probabilities
Win %
  • Guardians
    100%
  • Phillies
    0%
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Bryce Harper grounds out to first base to Kyle Manzardo.
Quick Box Score
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 A. Martínez RF4000001.0000.000
2 J. Ramírez 3B4010000.2500.500
3 K. Manzardo 1B11111001.0005.000
4 C. DeLauter DH1000000.0000.000
5 T. Bazzana 2B4000003.0000.000
6 B. Rocchio SS3010001.3330.666
7 S. Kwan LF3000001.0000.000
8 A. Hedges C2010010.5001.167
9 P. Halpin CF3000000.0000.000
Phillies Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 T. Turner SS4000001.0000.000
2 K. Schwarber DH4000004.0000.000
3 B. Harper 1B4010000.2500.750
4 A. Bohm 3B3000001.0000.000
5 B. Marsh LF3010002.3330.666
6 A. García RF3000002.0000.000
7 B. Stott 2B3010000.3330.666
8 J. Realmuto C3010001.3330.666
9 J. Crawford CF3000001.0000.000

Guardians vs. Phillies: Detailed Breakdown

Matchup Overview

  • Teams: Guardians vs. Phillies
  • Date: Friday, May 22, 2026
  • Time: 6:40 PM ET
  • Venue: Citizens Bank Park

Current Betting Odds

  • Spread: Phillies favored at -1.5
  • Total (Over/Under): 6.5
  • Moneyline Odds: Guardians +163, Phillies -160

Dimers' Win Probabilities

  • Guardians: 35%
  • Phillies: 65%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Guardians a win probability of 35%, while the Phillies have a win probability of 65%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Phillies are more likely to beat the Guardians in the MLB game at Citizens Bank Park on Friday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Guardians vs. Phillies predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.