Phillies vs. Cubs Prediction, Picks and Odds

Our detailed prediction and analysis for the Phillies vs. Cubs MLB game on April 22, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
Phillies
Kyle Backhus 0-0, 5.40 ERA
2
7
Wrigley Field
Cubs
Matthew Boyd 1-1, 6.75 ERA
Wrigley Field
1 2 3 4 5 6 7 8 9 RHE
Phillies
0 2 0 0 0 0 0 0 0 2 9 1
Cubs
1 1 2 0 2 0 0 1 X 7 13 1
Live Probabilities
Win %
  • Phillies
    0%
  • Cubs
    100%
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Rafael Marchán called out on strikes.
Quick Box Score
Phillies Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 K. Schwarber LF4000002.0000.000
2 T. Turner SS4010001.2500.750
3 B. Harper DH4000001.0000.000
4 F. Reyes 1B4110001.2500.500
5 A. García RF4010002.2500.500
6 A. Bohm 3B4120001.5001.000
7 B. Stott 2B2000001.0000.000
8 J. Crawford CF4011001.2500.500
9 R. Marchán C4010002.2500.500
Cubs Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 N. Hoerner 2B5110001.2000.400
2 A. Bregman 3B5130000.6001.600
3 I. Happ LF4112001.2500.500
4 S. Suzuki RF4122101.5001.750
5 M. Busch 1B4121101.5001.750
6 D. Swanson SS3000011.0000.250
7 M. Ballesteros DH4110000.2500.750
8 M. Amaya C4100001.0000.000
9 P. Crow-Armstrong CF4032001.7501.750

Phillies vs. Cubs: Detailed Breakdown

Matchup Overview

  • Teams: Phillies vs. Cubs
  • Date: Wednesday, April 22, 2026
  • Time: 7:40 PM ET
  • Venue: Wrigley Field

Current Betting Odds

  • Spread: Cubs favored at -1.5
  • Total (Over/Under): 7.5
  • Moneyline Odds: Phillies 36¢, Cubs 64¢

Dimers' Win Probabilities

  • Phillies: 40%
  • Cubs: 60%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Phillies a win probability of 40%, while the Cubs have a win probability of 60%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Cubs are more likely to beat the Phillies in the MLB game at Wrigley Field on Wednesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Phillies vs. Cubs predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.