Padres vs. Dodgers: MLB Prediction & Analysis

Our detailed prediction and analysis for the Padres vs. Dodgers MLB game on Tuesday, September 22, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
MLB
Add this game to My Favorites
Add this game to My Favorites
MLB sport icon
MLB
Padres
Michael King 12-9, 3.03 ERA
vs.
UNIQLO Field at Dodger Stadium
Dodgers
Yoshinobu Yamamoto 14-8, 2.51 ERA
UNIQLO Field at Dodger Stadium
Pre-Game Probabilities Last Update:

Moneyline

Moneyline
Win %
  • Padres
    43.1%
    PolymarketPolymarket
  • Dodgers
    56.9%
    NovigNovig

Padres vs. Dodgers: Detailed Breakdown

Matchup overview: MLB Tuesday

  • Teams: San Diego Padres vs. LA Dodgers Dodgers
  • Date: Tuesday, September 22, 2026
  • Time: 10:10PM ET
  • Venue: UNIQLO Field at Dodger Stadium

Current betting odds

  • Spread: Padres (-1.5, +165), Dodgers (+1.5, -170)
  • Moneyline: Padres +108, Dodgers -115
  • Total (Over/Under): 8.5 runs (+104/-112)

Dimers’ win probabilities

  • Padres: 43.4%
  • Dodgers: 56.6%

Dimers' predictive MLB model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Padres a win probability of 43.4%, while the Dodgers have a win probability of 56.6%.

Summary

According to our analysis, the Dodgers are more likely to beat the Padres in the MLB game at UNIQLO Field at Dodger Stadium on Tuesday. Discover the best run line, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Padres vs. Dodgers predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.