Cubs vs. Cardinals: MLB Prediction & Analysis

Our detailed prediction and analysis for the Cubs vs. Cardinals MLB game on Wednesday, July 29, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
Cubs
Matthew Boyd 6-1, 3.81 ERA
2
3
Busch Stadium
Cardinals
Dustin May 5-7, 4.59 ERA
Busch Stadium
2 3 4 5 6 7 8 9 10 RHE
Cubs
0 0 0 0 0 0 0 0 2 2 3 0
Cardinals
0 0 0 0 0 0 0 0 3 3 7 1
Live Probabilities
Win %
  • Cubs
    0%
  • Cardinals
    100%
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Ivan Herrera doubles to deep left center field. Jordan Walker scores. JJ Wetherholt scores.
Quick Box Score
Cubs Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 P. Crow-Armstrong CF5112100.2001.000
2 S. Suzuki RF3010020.3330.933
3 M. Busch 1B5000002.0000.000
4 A. Bregman 3B4010001.2500.750
5 I. Happ LF4000002.0000.000
6 J. Dean DH0000000.0000.000
7 C. Kelly C0000000.0000.000
8 D. Swanson SS4100001.0000.000
9 N. Hoerner 2B1000000.0000.000
Cardinals Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 J. Wetherholt 2B4100010.0000.200
2 J. Walker RF5111002.2000.400
3 I. Herrera DH5032001.6001.600
4 A. Burleson 1B4010002.2500.500
5 M. Winn SS4000003.0000.000
6 J. Fermín 3B3000011.0000.250
7 B. Torres LF0000000.0000.000
8 N. Church CF3100000.0000.250
9 L. Nootbaar PH10100001.0002.000

Cubs vs. Cardinals: Detailed Breakdown

Matchup overview: MLB Wednesday

  • Teams: CHI Cubs Cubs vs. St. Louis Cardinals
  • Date: Wednesday, July 29, 2026
  • Time: 7:45PM ET
  • Venue: Busch Stadium

Current betting odds

  • Spread: Cubs (-1.5, +163), Cardinals (+1.5, -170)
  • Moneyline: Cubs +100, Cardinals -102
  • Total (Over/Under): 7.5 runs (-108/+104)

Dimers’ win probabilities

  • Cubs: 50.8%
  • Cardinals: 49.2%

Dimers' predictive MLB model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cubs a win probability of 50.8%, while the Cardinals have a win probability of 49.2%.

Summary

According to our analysis, the Cubs are more likely to beat the Cardinals in the MLB game at Busch Stadium on Wednesday. Discover the best run line, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cubs vs. Cardinals predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.