Pirates vs. Reds prediction: Why Pittsburgh is favored to win Friday's MLB matchup [7/31/2026]

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Written by Dave Garofolo

Get Pittsburgh Pirates vs Cincinnati Reds predictions for MLB Friday.

Pittsburgh Pirates-Cincinnati Reds Predictions and Game Preview.
Pittsburgh Pirates vs. Cincinnati Reds MLB prediction for Friday, July 31, 2026.

The Cincinnati Reds and Pittsburgh Pirates will meet in MLB action at Great American Ball Park on Friday, starting at 6:10 PM ET.

Hunter Greene (2-2, 7.06 ERA) will start for the Reds, while the Pirates will counter with Paul Skenes (9-9, 3.66 ERA).

Dimers' proven MLB model gives the Pirates a slight edge with a 52.2% win probability over the Reds.

This article offers a closer look at Friday's Pirates vs. Reds matchup, including best bets and picks.

Pirates vs. Reds prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Friday's MLB game between the Pirates and Reds, forming part of our MLB predictions coverage.

Our leading predictive model currently gives the Pirates a 52.2% chance of beating the Reds.

According to our model, the Reds (+1.5) have a 60.1% chance of covering the run line, while the over/under total of 7.5 runs has a 56.9% chance of going over,.

 

Pirates vs. Reds odds [7/31/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Pirates Reds
Run Line -1.5 (+144) +1.5 (-147)
Moneyline -117 +115
Total o7.5 (-113) u7.5 (+108)

All odds are correct at the time of publication and are subject to change.

Pirates vs. Reds picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Reds +1.5 -147
Moneyline Reds hard_rock+115
Total Over 7.5 -113

According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Pirates vs. Reds game-day updates and essential details

Friday's MLB action between the Reds and Pirates at Great American Ball Park is scheduled to start at 6:10 PM ET.

Conclusion

We predict the Pirates, with a 52.2% win probability, will likely beat the Reds in Friday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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