Phillies vs. Cardinals prediction: Philadelphia favored to win Monday's MLB matchup [8/10/2026]

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Written by Dave Garofolo

Get Philadelphia Phillies vs St. Louis Cardinals predictions for MLB Monday.

Philadelphia Phillies-St. Louis Cardinals Predictions and Game Preview.
Philadelphia Phillies vs. St. Louis Cardinals MLB prediction for Monday, August 10, 2026.

The St. Louis Cardinals will face the Philadelphia Phillies, in what is expected to be a tight MLB game, at Busch Stadium on Monday, beginning at 7:45 PM ET.

Hunter Dobbins (2-2, 3.60 ERA) will be the starting pitcher for the Cardinals, pitting him against Andrew Painter (1-8, 6.48 ERA) for the Phillies.

Dimers' advanced MLB model gives the Phillies a slight edge with a 52.1% win probability over the Cardinals.

This article offers further insights into Monday's Phillies vs. Cardinals matchup, including best bets and picks.

Phillies vs. Cardinals prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Monday's MLB matchup between the Phillies and Cardinals, forming part of our MLB predictions coverage.

Our famous predictive model gives the Phillies a 52.1% chance of defeating the Cardinals.

According to our model, the Cardinals (+1.5) have a 59.6% chance of covering the run line, while the 9.5-run over/under has a 51.6% chance of going over,.

 

Phillies vs. Cardinals odds [8/10/2026]

We have researched the best MLB odds in America for this game, which are listed here:

  • Run Line: Phillies -1.5 (+150) / Cardinals +1.5 (-153)
  • Moneyline: Phillies -105, Cardinals +108

All odds are correct at the time of publication and are subject to change.

Phillies vs. Cardinals picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

  • Run line: Phillies -1.5 @ +150 via DraftKings
  • Moneyline: Phillies @ -105 via Bet365
  • Total: Over 9.5 @ +122 via Polymarket

According to our MLB best bets, the top play to make on this game is Over 9.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Phillies vs. Cardinals game-day updates and essential details

Monday's MLB action between the Cardinals and Phillies at Busch Stadium is scheduled to start at 7:45 PM ET.

Conclusion

We predict the Phillies, with a 52.1% win probability, will likely beat the Cardinals in Monday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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