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Read Article MLB strikeout projections today: Zack Wheeler leads top pitchers for September 22, 2026
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get baseball pitcher projections today guided by expert analysis of Tuesday's MLB slate.
Our MLB strikeout projections for Tuesday, September 22, 2026, feature Zack Wheeler of the Phillies as the top projected pitcher, according to Dimers Pro’s latest simulation data.
Today’s pitching projections are powered by our MLB model, which simulates every game thousands of times to estimate outcomes like strikeouts, outs recorded, and earned runs allowed.
Strikeout projections for September 22, 2026
See which pitchers join Wheeler on today’s leaderboard, with supporting projections included.
- Zack Wheeler (Phillies): 5.92 Ks, 17.22 outs, 1.89 earned runs, 4.33 hits
- Logan Gilbert (Mariners): 5.85 Ks, 15.55 outs, 1.63 earned runs, 3.70 hits
- MacKenzie Gore (Rangers): 5.36 Ks, 14.75 outs, 2.19 earned runs, 4.41 hits
- Drew Anderson (Tigers): 5.27 Ks, 15.17 outs, 2.20 earned runs, 4.46 hits
- Sean Manaea (Mets): 5.15 Ks, 15.31 outs, 2.50 earned runs, 4.89 hits
- Michael King (Padres): 4.86 Ks, 14.37 outs, 2.39 earned runs, 4.90 hits
- Michael Soroka (Diamondbacks): 4.80 Ks, 15.40 outs, 2.91 earned runs, 5.64 hits
- Dustin May (Brewers): 4.79 Ks, 16.46 outs, 2.67 earned runs, 5.42 hits
- Yusei Kikuchi (Angels): 4.78 Ks, 13.88 outs, 2.71 earned runs, 5.82 hits
- Cristian Javier (Astros): 4.72 Ks, 13.93 outs, 2.33 earned runs, 4.28 hits
For September 22, 2026, Wheeler tops today’s MLB strikeout projections with 5.92, followed by Logan Gilbert at 5.85. MacKenzie Gore, Drew Anderson and Sean Manaea round out the top five.
Want to explore the full slate? Check out today’s MLB pitcher projections to sort by strikeouts, outs, or earned runs for every starter.
Plus, check out the other side of the action with Tuesday's top 10 home run predictions.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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