Sep 16, 2026
Marlins vs. Diamondbacks prediction: Why Arizona is favored to win Wednesday's MLB matchup [9/16/2026]
Read Article Dodgers vs. Reds prediction: Why Dodgers are favored to win Wednesday's MLB matchup [9/16/2026]
Updated: | First published:
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Written by Dave Garofolo, Content Producer
Dimers' simulation model projects a 64.1% win probability for the Dodgers at Great American Ball Park.
The Cincinnati Reds will take on the Los Angeles Dodgers in MLB action at Great American Ball Park on Wednesday, starting at 6:40 PM ET.
Andrew Abbott (6-11, 4.78 ERA) will start for the Reds, pitting him against Blake Snell (4-1, 1.91 ERA) for the Dodgers.
Dimers' proven MLB model projects the Dodgers as the most likely winner in this Dodgers vs. Reds prediction.
This article offers a closer look at Wednesday's matchup, including best bets and picks.
Dodgers vs. Reds prediction and odds
Using trusted machine learning and data, we have re-simulated the result of Wednesday's MLB matchup between the Dodgers and Reds, forming part of our MLB predictions coverage.
Our famous predictive model gives the Dodgers a 64.1% chance of beating the Reds. According to our model, the Dodgers (-1.5) have a 52.6% chance of covering the run line, while the over/under total of 8.5 runs has a 58.1% chance of going over.
Latest betting odds
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Dodgers -1.5 (-117) / Reds +1.5 (+117)
- Moneyline: Dodgers -194, Reds +190
- Total: Over/Under 8.5 (+108/-105)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Reds +1.5 @ 46¢ via Polymarket
- Moneyline: Reds @ 34¢ via Novig
- Total: Over 8.5 @ 48¢ via Novig
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Wednesday's MLB action between the Reds and Dodgers at Great American Ball Park is scheduled to start at 6:40 PM ET.
- Who: Los Angeles Dodgers vs. Cincinnati Reds
- Date: Wednesday, September 16, 2026
- Time: 6:40 PM ET/3:40PM PT
- Venue: Great American Ball Park
Conclusion
We predict the Dodgers, with a 64.1% win probability, will likely beat the Reds in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
This article's predictions and probabilities are generated by Dimers' proprietary MLB prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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