Dodgers vs. Cubs prediction: Why Dodgers are favored to win Wednesday's MLB matchup [8/5/2026]

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Written by Dave Garofolo

Get Los Angeles Dodgers vs Chicago Cubs predictions for MLB Wednesday.

Los Angeles Dodgers-Chicago Cubs Predictions and Game Preview.
Los Angeles Dodgers vs. Chicago Cubs MLB prediction for Wednesday, August 5, 2026.

The Chicago Cubs and Los Angeles Dodgers will meet in MLB action at Wrigley Field on Wednesday, starting at 2:20 PM ET.

Shota Imanaga (7-9, 3.67 ERA) will start for the Cubs, while the Dodgers have opted for Eric Lauer (6-5, 4.50 ERA).

Dimers' proven MLB model gives the Dodgers a slight edge with a 52.4% win probability over the Cubs.

This article offers further insights into Wednesday's Dodgers vs. Cubs matchup, including best bets and picks.

Dodgers vs. Cubs prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Wednesday's MLB matchup between the Dodgers and Cubs, forming part of our MLB predictions coverage.

Our famous predictive model currently gives the Dodgers a 52.4% chance of defeating the Cubs.

According to our model, the Dodgers (+1.5) have a 66.5% chance of covering the run line, while the over/under total of 9.5 runs has a 53.4% chance of going over,.

 

Dodgers vs. Cubs odds [8/5/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Dodgers Cubs
Run Line +1.5 (-178) -1.5 (+170)
Moneyline +115 -108
Total o9.5 (-113) u9.5 (+113)

All odds are correct at the time of publication and are subject to change.

Dodgers vs. Cubs picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Dodgers +1.5 -178
Moneyline Dodgers +115
Total Over 9.5 -113

According to our best MLB bets, the top play to make on this game is Dodgers to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Dodgers vs. Cubs game-day updates and essential details

Wednesday's MLB matchup between the Cubs and Dodgers at Wrigley Field is scheduled to begin at 2:20 PM ET.

Conclusion

We predict the Dodgers, with a 52.4% win probability, will likely beat the Cubs in Wednesday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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