Reds vs. Cardinals prediction: St. Louis favored to win Sunday's MLB matchup [7/26/2026]

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Written by Dave Garofolo

Get Cincinnati Reds vs St. Louis Cardinals predictions for MLB Sunday.

Cincinnati Reds-St. Louis Cardinals Predictions and Game Preview.
Cincinnati Reds vs. St. Louis Cardinals MLB prediction for Sunday, July 26, 2026.

The St. Louis Cardinals and Cincinnati Reds will lock horns in MLB action at Busch Stadium on Sunday, starting at 2:15 PM ET.

The Cardinals will send Kyle Leahy (7-4, 3.59 ERA) to the mound, while the Reds will counter with Andrew Abbott (5-6, 3.89 ERA).

Based on updated simulation results, Dimers' proven MLB model gives the Cardinals a slight edge with a 54.6% win probability over the Reds.

This article offers a closer look at Sunday's Reds vs. Cardinals matchup, including best bets and picks.

Reds vs. Cardinals prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Sunday's MLB game between the Reds and Cardinals, forming part of our MLB predictions coverage.

Our leading predictive model currently gives the Cardinals a 54.6% chance of beating the Reds.

According to our model, the Reds (+1.5) have a 61.7% chance of covering the run line, while the over/under total of 8.5 runs has a 54.4% chance of going over,.

 

Reds vs. Cardinals odds [7/26/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Reds Cardinals
Run Line +1.5 (-170) -1.5 (+163)
Moneyline +122 -122
Total o8.5 (-105) u8.5 (+106)

All odds are correct at the time of publication and are subject to change.

Reds vs. Cardinals picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Cardinals -1.5 hard_rock+163
Moneyline Reds +122
Total Over 8.5 -105

According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Reds vs. Cardinals game-day updates and essential details

Sunday's MLB action between the Cardinals and Reds at Busch Stadium is scheduled to begin at 2:15 PM ET.

Conclusion

We predict the Cardinals, with a 54.6% win probability, will likely beat the Reds in Sunday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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