Cubs vs. Pirates prediction: Why Pittsburgh is favored to win Sunday's MLB matchup [7/26/2026]

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Written by Dave Garofolo

Get Chicago Cubs vs Pittsburgh Pirates predictions for MLB Sunday.

Chicago Cubs-Pittsburgh Pirates Predictions and Game Preview.
Chicago Cubs vs. Pittsburgh Pirates MLB prediction for Sunday, July 26, 2026.

The Pittsburgh Pirates will face the Chicago Cubs, in what is expected to be a close MLB game, at PNC Park on Sunday, commencing at 1:35 PM ET.

The Pirates will start Braxton Ashcraft (9-4, 3.95 ERA), while the Cubs have opted for Jameson Taillon (2-5, 5.38 ERA).

Based on updated simulations, Dimers' proven MLB model gives the Pirates a slight edge with a 53.6% win probability over the Cubs.

This article offers an expanded analysis of Sunday's Cubs vs. Pirates matchup, including best bets and picks.

Cubs vs. Pirates prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the result of Sunday's MLB matchup between the Cubs and Pirates, forming part of our MLB predictions coverage.

Our leading predictive model gives the Pirates a 53.6% chance of beating the Cubs.

According to our model, the Cubs (+1.5) have a 62.7% chance of covering the run line, while the 9-run over/under has a 53.3% chance of going over,.

 

Cubs vs. Pirates odds [7/26/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Cubs Pirates
Run Line +1.5 (-163) -1.5 (+163)
Moneyline +127 -125
Total o9 (+100) u9 (-110)

All odds are correct at the time of publication and are subject to change.

Cubs vs. Pirates picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Cubs +1.5 -163
Moneyline Cubs +127
Total Over 9 +100

According to our MLB best bets, the top play to make on this game is Over 9 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Cubs vs. Pirates game-day updates and essential details

Sunday's MLB game between the Pirates and Cubs at PNC Park is scheduled to commence at 1:35 PM ET.

Conclusion

We predict the Pirates, with a 53.6% win probability, will likely beat the Cubs in Sunday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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