Sep 22, 2026
MLB player props today: Tuesday's best props include Shota Imanaga [9/22/2026]
Read Article Diamondbacks vs. Rockies prediction: Why Arizona is favored to win Tuesday's MLB matchup [9/22/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Dimers' simulation model projects a 64.1% win probability for the Diamondbacks at Coors Field.
The Colorado Rockies will square off with the Arizona Diamondbacks in MLB action at Coors Field on Tuesday, beginning at 8:40 PM ET.
The Rockies will start Kyle Freeland (4-10, 6.38 ERA), while the Diamondbacks are going with Michael Soroka (8-5, 3.45 ERA).
Dimers' proven MLB model projects the Diamondbacks as the most likely winner in this Diamondbacks vs. Rockies prediction.
This article offers further insights into Tuesday's matchup, including best bets and picks.
Diamondbacks vs. Rockies prediction and odds
Using powerful machine learning and data, we have re-simulated the outcome of Tuesday's MLB game between the Diamondbacks and Rockies, forming part of our MLB predictions coverage.
Our leading predictive model gives the Diamondbacks a 64.1% chance of defeating the Rockies. According to our model, the Diamondbacks (-1.5) have a 54.0% chance of covering the run line, while the 10.5-run over/under has a 61.8% chance of going over.
Latest betting odds
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Diamondbacks -1.5 (-120) / Rockies +1.5 (+117)
- Moneyline: Diamondbacks -186, Rockies +178
- Total: Over/Under 10.5 (-117/+117)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Rockies +1.5 @ 46¢ via Polymarket
- Moneyline: Rockies @ 36¢ via Novig
- Total: Over 10.5 @ 54¢ via Polymarket
According to our MLB best bets, the top play to make on this game is Over 10.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Tuesday's MLB action between the Rockies and Diamondbacks at Coors Field is scheduled to begin at 8:40 PM ET.
- Who: Arizona Diamondbacks vs. Colorado Rockies
- Date: Tuesday, September 22, 2026
- Time: 8:40 PM ET/5:40PM PT
- Venue: Coors Field
Conclusion
We predict the Diamondbacks, with a 64.1% win probability, will likely beat the Rockies in Tuesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
This article's predictions and probabilities are generated by Dimers' proprietary MLB prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.
Every Bet, Every Game, Every Day Every plan unlocks every model, tool and insight, only the billing term changes.
MOST FLEXIBLE
Monthly billed monthly
$29.99
Month to month Pay as you go RECOMMENDED
6 Months one payment
$119.99 $149.99
6 months $20 per month Save $30.00 · 20% LIMITED TIME OFFER BEST VALUE
Annual first year
$169.99 $199.99
12 months $14.17 per month Save $30.00 · 15% LIMITED TIME OFFER Every plan includes
Full site access
iOS & Android app
AI bet assistant
Unlimited picks & predictions
Unlimited best bets & props
Unlimited player projections
Private Discord community
Cancel or pause anytime
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
Advertiser disclosure
