Louisville vs. Mississippi Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Louisville vs. Mississippi NCAAF game on September 6, 2026. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Louisville
Predicted score
24
:
29
Nissan Stadium
Mississippi
Nissan Stadium
Pre-Game Probabilities Last Update:

Spread

Louisville +6.5
Spread
  • Louisville
    52.6%
    FanaticsFanatics
  • Mississippi
    47.4%
    CaesarsCaesars

Louisville vs. Mississippi: Detailed Breakdown

Matchup Overview

  • Teams: Louisville vs. Mississippi
  • Date: Sunday, September 6, 2026
  • Time: 7:30 PM ET
  • Venue: Nissan Stadium

Current betting odds

  • Spread: Mississippi favored at -6.5
  • Total (Over/Under): 55.5
  • Moneyline Odds: Louisville +210, Mississippi -250

Dimers' win probabilities

  • Louisville: 37%
  • Mississippi: 63%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Louisville 24-29 Mississippi.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Louisville a win probability of 37%, while Mississippi has a win probability of 63%.

Summary

According to our analysis, Mississippi is more likely to beat Louisville in CFB action at Nissan Stadium on Sunday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Louisville vs. Mississippi predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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