College football picks today: Week 8 Thursday best bets include James Madison vs. Appalachian State play [10/22/2026]

profile-img
Written by Ryan Leaver

Get college football picks and best bets for Thursday, October 22, 2026.

College Football Best Bets.
These college football betting picks for October 22, 2026, are based on the latest odds and probabilities for Thursday's games.

Today’s college football picks for October 22, 2026 are here, with James Madison vs. Appalachian State and Liberty vs. Kennesaw State among the top plays identified by our model across Thursday’s college football action.

Dimers’ predictive analytics engine runs 24/7, going over the latest football odds to find top betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of college football picks tonight [10/22, updated 3:38AM ET]

Below, you’ll find today’s college football best bets, ranked by edge for Thursday, October 22, 2026.

Appalachian State +11.5 (-104)

Our model has identified value on Appalachian State +11.5 at 51¢ odds. A 54.9% probability produces an edge of 3.9%, making this the strongest play for today's college football slate.

 

Kennesaw State +8.5 (+108)

Kennesaw State +8.5 carries a 3.9% edge and a probability of 51.9% at 48¢ odds, according to our model.

 

Memphis ML (78¢)

Memphis ML at 78¢ odds shows a 2.2% edge, supported by a 80.2% probability in simulations.

 

NCAAF best bets summary: Thursday, 10/22/2026

As of 3:38AM ET, here are our top college football bets by edge recommended by our model:

Matchup Bet Odds Edge Prob.
James Madison vs. Appalachian State Appalachian State +11.5 51¢ @ Novig 3.9% 54.9%
Liberty vs. Kennesaw State Kennesaw State +8.5 48¢ @ Novig 3.9% 51.9%
East Carolina vs. Memphis Memphis ML 78¢ @ Novig 2.2% 80.2%
 

List of upcoming college football games to bet on now

College football offer for Week 8

Make the most of the picks in this article, including Appalachian State +11.5, with the Underdog Fantasy offer below:


Conclusion

Our college football best bets are locked and loaded for October 22, 2026, featuring plays such as Appalachian State +11.5 vs. James Madison and Kennesaw State +8.5. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.

Every Bet, Every Game, Every Day Every plan unlocks every model, tool and insight, only the billing term changes.
MOST FLEXIBLE
Monthly billed monthly
$29.99
Month to month Pay as you go
Renews monthly. Cancel or pause anytime.
RECOMMENDED
6 Months one payment
$119.99 $149.99
6 months $20 per month Save 33% vs monthly LIMITED TIME OFFER - SAVE $30
Renews in 6 months at the standard price.
BEST VALUE
Annual first year
$169.99 $199.99
12 months $14.17 per month Save 53% vs monthly LIMITED TIME OFFER - SAVE $30
Renews yearly at the standard price.
Every plan includes
Full site access
iOS & Android app
AI bet assistant
Unlimited picks & predictions
Unlimited best bets & props
Unlimited player projections
Private Discord community
Cancel or pause anytime
profile-img
Written by
Ryan Leaver
Senior Editor

Ryan Leaver specializes in sports betting analysis across the NBA, NFL, college football, college basketball, and soccer. Drawing on advanced statistical models, simulations, and historical data, he produces game previews, betting picks, player prop analysis, and futures coverage to help bettors make more informed decisions.

Advertiser disclosure

Related Articles

More Articles
Dimers Sports
College football player props today: Week 8 Thursday best props include TJ Engleman Jr. [10/22/2026]
Read Article
Dimers Sports
New Mexico State vs. Sam Houston State prediction favors New Mexico State to win in college football Week 8 [2026]
Read Article
Dimers Sports
College football player props today: Week 8 Wednesday best props include Chris Reed [10/21/2026]
Read Article